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Clinical and translational advances in ovarian cancer therapy
Ovarian cancer is an aggressive disease that is frequently detected at advanced stages and
is initially very responsive to platinum-based chemotherapy. However, the majority of …
is initially very responsive to platinum-based chemotherapy. However, the majority of …
[HTML][HTML] Selective estrogen receptor modulators (SERMs) and selective estrogen receptor degraders (SERDs) in cancer treatment
HK Patel, T Bihani - Pharmacology & therapeutics, 2018 - Elsevier
Breast cancer is the most frequently diagnosed cancer in women, with estrogen receptor
positive (ER+) breast cancer making up approximately 75% of all breast cancers diagnosed …
positive (ER+) breast cancer making up approximately 75% of all breast cancers diagnosed …
The genomic and immune landscape of long-term survivors of high-grade serous ovarian cancer
DW Garsed, A Pandey, S Fereday, CJ Kennedy… - Nature …, 2022 - nature.com
Fewer than half of all patients with advanced-stage high-grade serous ovarian cancers
(HGSCs) survive more than five years after diagnosis, but those who have an exceptionally …
(HGSCs) survive more than five years after diagnosis, but those who have an exceptionally …
[HTML][HTML] Molecular characteristics and clinical behaviour of epithelial ovarian cancers
RL Hollis - Cancer letters, 2023 - Elsevier
Ovarian carcinoma (OC) is an umbrella term for multiple distinct diseases (histotypes), each
with their own developmental origins, clinical behaviour and molecular profile. Accordingly …
with their own developmental origins, clinical behaviour and molecular profile. Accordingly …
The evolution of ovarian carcinoma subclassification
M Köbel, EY Kang - Cancers, 2022 - mdpi.com
Simple Summary Historically, cancers presenting with their main tumor mass in the ovary
have been classified as ovarian carcinomas (a concise term for epithelial ovarian cancer) …
have been classified as ovarian carcinomas (a concise term for epithelial ovarian cancer) …
Dose-response association of CD8+ tumor-infiltrating lymphocytes and survival time in high-grade serous ovarian cancer
EL Goode, MS Block, KR Kalli, RA Vierkant… - JAMA …, 2017 - jamanetwork.com
Importance Cytotoxic CD8+ tumor-infiltrating lymphocytes (TILs) participate in immune
control of epithelial ovarian cancer; however, little is known about prognostic patterns of …
control of epithelial ovarian cancer; however, little is known about prognostic patterns of …
Paradigm shift: a comprehensive review of ovarian cancer management in an era of advancements
V Tavares, IS Marques, IG Melo, J Assis… - International journal of …, 2024 - mdpi.com
Ovarian cancer (OC) is the female genital malignancy with the highest lethality. Patients
present a poor prognosis mainly due to the late clinical presentation allied with the common …
present a poor prognosis mainly due to the late clinical presentation allied with the common …
Heat shock proteins and HSF1 in cancer
AM Cyran, A Zhitkovich - Frontiers in oncology, 2022 - frontiersin.org
Fitness of cells is dependent on protein homeostasis which is maintained by cooperative
activities of protein chaperones and proteolytic machinery. Upon encountering protein …
activities of protein chaperones and proteolytic machinery. Upon encountering protein …
Hormonal maintenance therapy for women with low-grade serous cancer of the ovary or peritoneum
DM Gershenson, DC Bodurka, RL Coleman… - Journal of Clinical …, 2017 - ascopubs.org
Purpose The purpose of this study was to examine outcomes associated with hormonal
maintenance therapy (HMT) compared with routine observation (OBS) after primary …
maintenance therapy (HMT) compared with routine observation (OBS) after primary …
An immunohistochemical algorithm for ovarian carcinoma ty**
There are 5 major histotypes of ovarian carcinomas. Diagnostic ty** criteria have evolved
over time, and past cohorts may be misclassified by current standards. Our objective was to …
over time, and past cohorts may be misclassified by current standards. Our objective was to …