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Viral persistence, reactivation, and mechanisms of long COVID
The COVID-19 global pandemic caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection has infected hundreds of millions of individuals …
coronavirus 2 (SARS-CoV-2) infection has infected hundreds of millions of individuals …
Impact of the Human Cell Atlas on medicine
Single-cell atlases promise to provide a 'missing link'between genes, diseases and
therapies. By identifying the specific cell types, states, programs and contexts where disease …
therapies. By identifying the specific cell types, states, programs and contexts where disease …
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2
Preventing SARS-CoV-2 infection by modulating viral host receptors, such as angiotensin-
converting enzyme 2 (ACE2), could represent a new chemoprophylactic approach for …
converting enzyme 2 (ACE2), could represent a new chemoprophylactic approach for …
Cross-tissue immune cell analysis reveals tissue-specific features in humans
Despite their crucial role in health and disease, our knowledge of immune cells within
human tissues remains limited. We surveyed the immune compartment of 16 tissues from 12 …
human tissues remains limited. We surveyed the immune compartment of 16 tissues from 12 …
Mechanisms of SARS-CoV-2 entry into cells
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells
ABSTRACT The novel SARS-CoV-2 Omicron variant (B. 1.1. 529), first found in early
November 2021, has sparked considerable global concern and it has> 50 mutations, many …
November 2021, has sparked considerable global concern and it has> 50 mutations, many …
Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb
M Khan, SJ Yoo, M Clijsters, W Backaert, A Vanstapel… - Cell, 2021 - cell.com
Anosmia, the loss of smell, is a common and often the sole symptom of COVID-19. The onset
of the sequence of pathobiological events leading to olfactory dysfunction remains obscure …
of the sequence of pathobiological events leading to olfactory dysfunction remains obscure …
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress
syndrome and multiple organ failure,,–, but little is known about its pathophysiology. Here …
syndrome and multiple organ failure,,–, but little is known about its pathophysiology. Here …
[HTML][HTML] Post-acute COVID-19 syndrome
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen
responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in …
responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in …
Age-specific nasal epithelial responses to SARS-CoV-2 infection
MNJ Woodall, AM Cujba, KB Worlock, KM Case… - Nature …, 2024 - nature.com
Children infected with SARS-CoV-2 rarely progress to respiratory failure. However, the risk
of mortality in infected people over 85 years of age remains high. Here we investigate …
of mortality in infected people over 85 years of age remains high. Here we investigate …