Growth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane

EA Vitriol, JQ Zheng - Neuron, 2012 - cell.com
Growth cones, found at the tip of axonal projections, are the sensory and motile organelles
of develo** neurons that enable axon pathfinding and target recognition for precise wiring …

Regulation of axonal outgrowth and pathfinding by integrin–ECM interactions

JP Myers, M Santiago‐Medina… - Developmental …, 2011 - Wiley Online Library
Develo** neurons use a combination of guidance cues to assemble a functional neural
network. A variety of proteins immobilized within the extracellular matrix (ECM) provide …

AHNAK: the giant jack of all trades

TA Davis, B Loos, AM Engelbrecht - Cellular signalling, 2014 - Elsevier
The nucleoprotein AHNAK is an unusual and somewhat mysterious scaffolding protein
characterised by its large size of approximately 700 kDa. Several aspects of this protein …

Lignosus rhinocerus (Cooke) Ryvarden: A Medicinal Mushroom That Stimulates Neurite Outgrowth in PC‐12 Cells

LF Eik, M Naidu, P David, KH Wong… - Evidence‐Based …, 2012 - Wiley Online Library
A national treasure mushroom, Lignosus rhinocerus, has been used to treat variety of
ailments by local and indigenous communities in Malaysia. The aim of this study was to …

Astrocyte stellation, a process dependent on Rac1 is sustained by the regulated exocytosis of enlargeosomes

G Racchetti, R D'Alessandro, J Meldolesi - Glia, 2012 - Wiley Online Library
Cultured astrocytes exhibit a flat/epitelioid phenotype much different from the star‐like
phenotype of tissue astrocytes. Upon exposure to treatments that affect the small GTPase …

[HTML][HTML] Secretion of VGF relies on the interplay between LRRK2 and post-Golgi v-SNAREs

F Filippini, S Nola, A Zahraoui, K Roger, M Esmaili… - Cell Reports, 2023 - cell.com
The neuropeptide VGF was recently proposed as a neurodegeneration biomarker. The
Parkinson's disease-related protein leucine-rich repeat kinase 2 (LRRK2) regulates …

Vesicular traffic in cell navigation

K Zylbersztejn, T Galli - The FEBS journal, 2011 - Wiley Online Library
Cell navigation is the process whereby cells or cytoplasmic extensions are guided from one
point to another in multicellular organisms or, in the case of unicellular eukaryotic …

Cell surface dynamics–how Rho GTPases orchestrate the interplay between the plasma membrane and the cortical cytoskeleton

I de Curtis, J Meldolesi - Journal of cell science, 2012 - journals.biologists.com
Small GTPases are known to regulate hundreds of cell functions. In particular, Rho family
GTPases are master regulators of the cytoskeleton. By regulating actin nucleation …

Role of the Sec22b–E-Syt complex in neurite growth and ramification

A Gallo, L Danglot, F Giordano, B Hewlett… - Journal of cell …, 2020 - journals.biologists.com
Axons and dendrites are long and often ramified neurites that need particularly intense
plasma membrane (PM) expansion during the development of the nervous system. Neurite …

SNAREs and developmental disorders

BL Tang - Journal of cellular physiology, 2021 - Wiley Online Library
Members of the soluble N‐ethylmaleimide‐sensitive factor attachment protein receptor
(SNARE) family mediate membrane fusion processes associated with vesicular trafficking …