Haematopoietic and immune defects associated with GATA2 mutation
Heterozygous familial or sporadic GATA 2 mutations cause a multifaceted disorder,
encompassing susceptibility to infection, pulmonary dysfunction, autoimmunity …
encompassing susceptibility to infection, pulmonary dysfunction, autoimmunity …
The GATA factor revolution in hematology
KR Katsumura, EH Bresnick… - Blood, The Journal …, 2017 - ashpublications.org
The discovery of the GATA binding protein (GATA factor) transcription factor family
revolutionized hematology. Studies of GATA proteins have yielded vital contributions to our …
revolutionized hematology. Studies of GATA proteins have yielded vital contributions to our …
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
N Cabezas-Wallscheid, D Klimmeck, J Hansson… - Cell stem cell, 2014 - cell.com
In this study, we present integrated quantitative proteome, transcriptome, and methylome
analyses of hematopoietic stem cells (HSCs) and four multipotent progenitor (MPP) …
analyses of hematopoietic stem cells (HSCs) and four multipotent progenitor (MPP) …
Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo
The adult blood system is established by hematopoietic stem cells (HSCs), which arise
during development from an endothelial-to-hematopoietic transition of cells comprising the …
during development from an endothelial-to-hematopoietic transition of cells comprising the …
[HTML][HTML] Developmental hematopoiesis: ontogeny, genetic programming and conservation
A Ciau-Uitz, R Monteiro, A Kirmizitas, R Patient - Experimental hematology, 2014 - Elsevier
Hematopoietic stem cells (HSCs) sustain blood production throughout life and are of pivotal
importance in regenerative medicine. Although HSC generation from pluripotent stem cells …
importance in regenerative medicine. Although HSC generation from pluripotent stem cells …
Endothelial-to-haematopoietic transition: an update on the process of making blood
K Ottersbach - Biochemical Society Transactions, 2019 - portlandpress.com
The first definitive blood cells during embryogenesis are derived from endothelial cells in a
highly conserved process known as endothelial-to-haematopoietic transition (EHT). This …
highly conserved process known as endothelial-to-haematopoietic transition (EHT). This …