Poly (lactic-co-glycolic acid)(PLGA) is one of the most effective biodegradable polymeric
nanoparticles (NPs). It has been approved by the US FDA to use in drug delivery systems …

Polymeric drug-loaded nanoparticles have been extensively studied in the field of drug
delivery. Biodistribution depends on the physicochemical properties of particles, especially …

Due to the abundance of microplastics in the environment, research about its possible
adverse effects is increasing exponentially. Most studies investigating the effect of …

The effectiveness of anticancer agents may be hindered by low solubility in water, poor
permeability, and high efflux from cells. Nanomaterials have been used to enable drug …

Background: Aggregated biotherapeutics have the potential to induce an immune response.
Results: Aggregates can enhance innate and adaptive immune responses of PBMC …

Nanotoxicology studies require investigations of several physico-chemical aspects of the
particle/body fluid interaction, here described by reviewing recent literature in the light of …

Drug delivery has been greatly improved over the years by means of chemical and physical
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …

Biodegradable microspheres (MS) have proven to be very useful antigen delivery systems
that are ingested by immunocompetent cells and provide prolonged antigen release and …

Bacterial infection caused by intracellular pathogens, such as Mycobacterium, Salmonella,
and Brucella, is a burgeoning global health epidemic that necessitates urgent action …

Many infectious diseases are caused by facultative organisms that are able to survive in
phagocytic cells. The intracellular location of these microorganisms protects them from the …