Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents,
including mice and rats, with important spatial and textural information about their immediate …

The motor cortex is a large frontal structure in the cerebral cortex of eutherian mammals. A
vast array of evidence implicates the motor cortex in the volitional control of motor output, but …

Adaptive behaviour crucially depends on flexible decision-making, which in mammals relies
on the frontal cortex, specifically the orbitofrontal cortex (OFC),,,,,,,–. How OFC encodes …

Humans detect skin temperature changes that are perceived as warm or cool. Like humans,
mice report forepaw skin warming with perceptual thresholds of less than 1° C and do not …

Spontaneous fluctuations in hemodynamic signals in the absence of a task or overt
stimulation are used to infer neural activity. We tested this coupling by simultaneously …

The location of short-term memory in mammalian neocortex remains elusive. Here we show
that distinct neocortical areas maintain short-term memory depending on behavioral …

Cortical neurons process information on a background of spontaneous, ongoing activity with
distinct spatiotemporal profiles defining different cortical states. During wakefulness, cortical …

The neuronal mechanisms generating a delayed motor response initiated by a sensory cue
remain elusive. Here, we tracked the precise sequence of cortical activity in mice …

To advance the measurement of distributed neuronal population representations of targeted
motor actions on single trials, we developed an optical method (COSMOS) for tracking …

Motor cortex (M1) lesions result in motor impairments, yet how M1 contributes to the control
of movement remains controversial. To investigate the role of M1 in sensory guided motor …