Chromatin provides both a means to accommodate a large amount of genetic material in a
small space and a means to package the same genetic material in different chromatin states …

RecA/Rad51 catalyzed pairing of homologous DNA strands, initiated by polymerization of
the recombinase on single-stranded DNA (ssDNA), is a universal feature of homologous …

The CRISPR-associated enzyme Cas9 is an RNA-guided endonuclease that uses RNA:
DNA base-pairing to target and cleave foreign DNA as part of an adaptive immune system in …

The spatial organization, correct expression, repair, and segregation of eukaryotic genomes
depend on cohesin, ring‐shaped protein complexes that are thought to function by …

Cohesin is essential for the hierarchical organization of the eukaryotic genome and plays
key roles in many aspects of chromosome biology. The conformation of cohesin bound to …

DNA intercalators are widely used as fluorescent probes to visualize DNA and DNA
transactions in vivo and in vitro. It is well known that they perturb DNA structure and stability …

The parABS system is a widely employed mechanism for plasmid partitioning and
chromosome segregation in bacteria. ParB binds to parS sites on plasmids and …

The repair of DNA double-strand breaks (DSBs) is essential for cell viability and important
for homologous genetic recombination. In enteric bacteria such as Escherichia coli, the …

Molecular motors are diverse enzymes that transduce chemical energy into mechanical
work and, in doing so, perform critical cellular functions such as DNA replication and …

Genetic recombination in all kingdoms of life initiates when helicases and nucleases
process (resect) the free DNA ends to expose single-stranded DNA (ssDNA) overhangs …