Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

J Nicolas, S Mura, D Brambilla, N Mackiewicz… - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

Recent advances in PEG–PLA block copolymer nanoparticles

RZ **ao, ZW Zeng, GL Zhou, JJ Wang… - International journal …, 2010 - Taylor & Francis
Due to their small particle size and large and modifiable surface, nanoparticles have unique
advantages compared with other drug carriers. As a research focus in recent years …

Pharmacokinetics of metronomic chemotherapy: a neglected but crucial aspect

G Bocci, RS Kerbel - Nature Reviews Clinical Oncology, 2016 - nature.com
Metronomic chemotherapy describes the close, regular administration of chemotherapy
drugs at less-toxic doses over prolonged periods of time. In 2015, the results of randomized …

The pharmacological bases of the antiangiogenic activity of paclitaxel

G Bocci, A Di Paolo, R Danesi - Angiogenesis, 2013 - Springer
In the mid 1990s, researchers began to investigate the antiangiogenic activity of paclitaxel
as a possible additional mechanism contributing to its antineoplastic activity in vivo. In the …

Drug delivery systems for differential release in combination therapy

H Zhang, G Wang, H Yang - Expert opinion on drug delivery, 2011 - Taylor & Francis
Introduction: Combination therapy with multiple therapeutic agents has wide applicability in
medical and surgical treatment, especially in the treatment of cancer. Thus, new drug …

Emerging uses of PLA–PEG copolymer in cancer drug delivery

R Mundel, T Thakur, M Chatterjee - 3 Biotech, 2022 - Springer
Traditional therapies need high systematic dosages that not only destroys cancerous cells
but also healthy cells. To overcome this problem recent advancement in nanotechnology …

[HTML][HTML] In vivo evaluation of antitumoral and antiangiogenic effect of imiquimod-loaded polymeric nanoparticles

MF Dias, BCP de Figueiredo, J Teixeira-Neto… - Biomedicine & …, 2018 - Elsevier
The chemotherapeutic agent imiquimod (Imq) is used to treat skin cancers, the most
common type of human cancer. However, the high incidence of local and systemic side …

Characterization, pharmacokinetics and disposition of novel nanoscale preparations of paclitaxel

C Wang, YJ Wang, YJ Wang, M Fan, F Luo… - International journal of …, 2011 - Elsevier
Polymeric nanoparticles (NPs) have great potential application in achieving targeted
delivery of anticancer drugs. Paclitaxel (PTX) loaded NPs were developed using …

Antioxidant Poly(lactic-co-glycolic) Acid Nanoparticles Made with α-Tocopherol–Ascorbic Acid Surfactant

CE Astete, D Dolliver, M Whaley, L Khachatryan… - ACS …, 2011 - ACS Publications
The goal of the study was to synthesize a surfactant made of α-tocopherol (vitamin E) and
ascorbic acid (vitamin C) of antioxidant properties dubbed as EC, and to use this surfactant …

[PDF][PDF] Folate-decorated, endostatin-loaded, nanoparticles for anti-proliferative chemotherapy in esophaegeal squamous cell carcinoma

SA Adeyemi, YE Choonara, P Kumar… - Biomedicine & …, 2019 - drive.google.com
This study aims to design and synthesize Endostatin (ENT)-loaded nanoparticles using Folic
acid (FA) as a driver for targeted anti-proliferative chemotherapy in Esophageal Squamous …