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Tumour predisposition and cancer syndromes as models to study gene–environment interactions
Cell division and organismal development are exquisitely orchestrated and regulated
processes. The dysregulation of the molecular mechanisms underlying these processes …
processes. The dysregulation of the molecular mechanisms underlying these processes …
Mitochondria and oxygen homeostasis
Molecular oxygen possesses a dual nature due to its highly reactive free radical property: it
is capable of oxidizing metabolic substrates to generate cellular energy, but can also serve …
is capable of oxidizing metabolic substrates to generate cellular energy, but can also serve …
Explainable artificial intelligence (XAI) for exploring spatial variability of lung and bronchus cancer (LBC) mortality rates in the contiguous USA
Abstract Machine learning (ML) has demonstrated promise in predicting mortality; however,
understanding spatial variation in risk factor contributions to mortality rate requires …
understanding spatial variation in risk factor contributions to mortality rate requires …
[HTML][HTML] Histologic lung cancer incidence rates and trends vary by race/ethnicity and residential county
KA Houston, KA Mitchell, J King, A White… - Journal of Thoracic …, 2018 - Elsevier
Introduction Lung cancer incidence is higher among non-Hispanic (NH) blacks than among
the NH white and Hispanic populations in the United States. However, national cancer …
the NH white and Hispanic populations in the United States. However, national cancer …
Morphological and molecular-biological features of glioblastoma progression in tolerant and susceptible to hypoxia Wistar rats
DS Dzhalilova, NA Zolotova, VA Mkhitarov… - Scientific reports, 2023 - nature.com
Hypoxia is a major pathogenetic factor in many cancers. Individual resistance to suboptimal
oxygen availability is subject to broad variation and its possible role in tumorigenesis …
oxygen availability is subject to broad variation and its possible role in tumorigenesis …
HIF-dependent mechanisms of relationship between hypoxia tolerance and tumor development
DS Dzhalilova, OV Makarova - Biochemistry (Moscow), 2021 - Springer
Oxygen deficiency is one of the key pathogenetic factors determining development and
severity of many diseases, including inflammatory, infectious diseases, and cancer. Lack of …
severity of many diseases, including inflammatory, infectious diseases, and cancer. Lack of …
Revisiting the COVID-19 fatality rate and altitude association through a comprehensive analysis
The emergence of COVID-19 virus has led to a pandemic with staggering morbidity and
mortality. There is evidence showing that pre-existing conditions and environmental factors …
mortality. There is evidence showing that pre-existing conditions and environmental factors …
Influence of the atmospheric environment on spatial variation of lung cancer incidence in China
H Yu, Y Wang, X Yue, H Zhang - Plos one, 2024 - journals.plos.org
Conducting this research contributes to a deeper understanding of the correlation between
atmospheric environmental quality and lung cancer incidence, and provides the scientific …
atmospheric environmental quality and lung cancer incidence, and provides the scientific …
High altitude and cancer mortality
M Thiersch, ER Swenson - High altitude medicine & biology, 2018 - liebertpub.com
Abstract Thiersch, Markus, and Erik R. Swenson. High altitude and cancer mortality. High Alt
Med Biol 19: 116–123, 2018.—Humans living at high altitude (HA) are exposed to chronic …
Med Biol 19: 116–123, 2018.—Humans living at high altitude (HA) are exposed to chronic …
[HTML][HTML] The oxygen transport triad in high-altitude pulmonary edema: a perspective from the high Andes
G Zubieta-Calleja, N Zubieta-DeUrioste - International Journal of …, 2021 - mdpi.com
Acute high-altitude illnesses are of great concern for physicians and people traveling to high
altitude. Our recent article “Acute Mountain Sickness, High-Altitude Pulmonary Edema and …
altitude. Our recent article “Acute Mountain Sickness, High-Altitude Pulmonary Edema and …