Use of Bombyx mori silk fibroin in tissue engineering: From cocoons to medical devices, challenges, and future perspectives

A Bucciarelli, A Motta - Biomaterials Advances, 2022 - Elsevier
Silk fibroin has become a prominent material in tissue engineering (TE) over the last 20
years with almost 10,000 published works spanning in all the TE applications, from skeleton …

Emerging roles of hyaluronic acid bioscaffolds in tissue engineering and regenerative medicine

M Hemshekhar, RM Thushara… - International Journal of …, 2016 - Elsevier
Hyaluronic acid (HA), is a glycosaminoglycan comprised of repeating disaccharide units of
N-acetyl-d-glucosamine and d-glucuronic acid. HA is synthesized by hyaluronan synthases …

Enzymatically crosslinked silk-hyaluronic acid hydrogels

NR Raia, BP Partlow, M McGill, EP Kimmerling… - Biomaterials, 2017 - Elsevier
In this study, silk fibroin and hyaluronic acid (HA) were enzymatically crosslinked to form
biocompatible composite hydrogels with tunable mechanical properties similar to that of …

Epicardial application of cardiac progenitor cells in a 3D-printed gelatin/hyaluronic acid patch preserves cardiac function after myocardial infarction

R Gaetani, DAM Feyen, V Verhage, R Slaats… - Biomaterials, 2015 - Elsevier
Cardiac cell therapy suffers from limitations related to poor engraftment and significant cell
death after transplantation. In this regard, ex vivo tissue engineering is a tool that has been …

A patch of detachable hybrid microneedle depot for localized delivery of mesenchymal stem cells in regeneration therapy

KJ Lee, Y Xue, J Lee, HJ Kim, Y Liu… - Advanced Functional …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been widely used for regenerative therapy. In most
current clinical applications, MSCs are delivered by injection but face significant issues with …

Natural biomaterials for cardiac tissue engineering: a highly biocompatible solution

QA Majid, ATR Fricker, DA Gregory… - Frontiers in …, 2020 - frontiersin.org
Cardiovascular diseases (CVD) constitute a major fraction of the current major global
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …

Cell encapsulation: Overcoming barriers in cell transplantation in diabetes and beyond

M Farina, JF Alexander, U Thekkedath, M Ferrari… - Advanced drug delivery …, 2019 - Elsevier
Cell-based therapy is emerging as a promising strategy for treating a wide range of human
diseases, such as diabetes, blood disorders, acute liver failure, spinal cord injury, and …

Mesenchymal stem cells in cardiac regeneration: a detailed progress report of the last 6 years (2010–2015)

A Singh, A Singh, D Sen - Stem cell research & therapy, 2016 - Springer
Mesenchymal stem cells have been used for cardiovascular regenerative therapy for
decades. These cells have been established as one of the potential therapeutic agents …

Can we engineer a human cardiac patch for therapy?

J Zhang, W Zhu, M Radisic… - Circulation …, 2018 - ahajournals.org
Some of the most significant leaps in the history of modern civilization—the development of
article in China, the steam engine, which led to the European industrial revolution, and the …

A multilayered scaffold of a chitosan and gelatin hydrogel supported by a PCL core for cardiac tissue engineering

S Pok, JD Myers, SV Madihally, JG Jacot - Acta biomaterialia, 2013 - Elsevier
A three-dimensional scaffold composed of self-assembled polycaprolactone (PCL)
sandwiched in a gelatin–chitosan hydrogel was developed for use as a biodegradable …