Lipid nanoparticle (LNP) enables mRNA delivery for cancer therapy
Messenger RNA (mRNA) has received great attention in the prevention and treatment of
various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA …
various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA …
Immune cell Membrane‐Coated biomimetic nanoparticles for targeted cancer therapy
Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …
Lipid nanoparticle-mediated lymph node–targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response
The targeted delivery of messenger RNA (mRNA) to desired organs remains a great
challenge for in vivo applications of mRNA technology. For mRNA vaccines, the targeted …
challenge for in vivo applications of mRNA technology. For mRNA vaccines, the targeted …
From influenza to COVID-19: Lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases
Vaccination represents the best line of defense against infectious diseases and is crucial in
curtailing pandemic spread of emerging pathogens to which a population has limited …
curtailing pandemic spread of emerging pathogens to which a population has limited …
Opportunities and challenges in the delivery of mRNA-based vaccines
In the past few years, there has been increasing focus on the use of messenger RNA
(mRNA) as a new therapeutic modality. Current clinical efforts encompassing mRNA-based …
(mRNA) as a new therapeutic modality. Current clinical efforts encompassing mRNA-based …
Cancer nanotechnology: current status and perspectives
JA Kemp, YJ Kwon - Nano convergence, 2021 - Springer
Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …
end in sight. Cancer treatments have significantly progressed, but the need to increase …
Natural killer cells: a promising immunotherapy for cancer
J Chu, F Gao, M Yan, S Zhao, Z Yan, B Shi… - Journal of translational …, 2022 - Springer
As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …
recently gained attention as an important type of innate immune regulatory cell. NK cells can …
Progress and prospects on vaccine development against SARS-CoV-2
J Zhang, H Zeng, J Gu, H Li, L Zheng, Q Zou - Vaccines, 2020 - mdpi.com
In December 2019, the outbreak of pneumonia caused by a novel coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a serious pandemic in China …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a serious pandemic in China …
Current developments and challenges of mRNA vaccines
mRNA vaccines have brought about a great revolution in the vaccine fields owing to their
simplicity and adaptability in antigen design, potential to induce both humoral and cell …
simplicity and adaptability in antigen design, potential to induce both humoral and cell …
[HTML][HTML] Biological drug and drug delivery-mediated immunotherapy
The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …
inflammation, and some autoimmune diseases are closely linked to the immune system …