Opportunities and challenges for co-delivery nanomedicines based on combination of phytochemicals with chemotherapeutic drugs in cancer treatment

Q Gao, J Feng, W Liu, C Wen, Y Wu, Q Liao… - Advanced drug delivery …, 2022 - Elsevier
The therapeutic limitations such as insufficient efficacy, drug resistance, metastasis, and
undesirable side effects are frequently caused by the long duration monotherapy based on …

[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches

M Ashrafizadeh, M Delfi, A Zarrabi, A Bigham… - Journal of controlled …, 2022 - Elsevier
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …

Phytosomes as innovative delivery systems for phytochemicals: A comprehensive review of literature

M Barani, E Sangiovanni, M Angarano… - International journal …, 2021 - Taylor & Francis
Nowadays, medicinal herbs and their phytochemicals have emerged as a great therapeutic
option for many disorders. However, poor bioavailability and selectivity might limit their …

CD44-targeted nanocarrier for cancer therapy

P Kesharwani, R Chadar, A Sheikh, WY Rizg… - Frontiers in …, 2022 - frontiersin.org
Cluster of differentiation 44 (CD44) is a cell surface glycoprotein overexpressed in varieties
of solid tumors including pancreatic, breast, ovary, brain, and lung cancers. It is a multi …

Advances in Stigmasterol on its anti-tumor effect and mechanism of action

X Zhang, J Wang, L Zhu, X Wang, F Meng, L **a… - Frontiers in …, 2022 - frontiersin.org
Stigmasterol is a phytosterol derived from multiple herbaceous plants such as herbs,
soybean and tobacco, and it has received much attention for its various pharmacological …

[HTML][HTML] Recent advances in phytochemical-based Nano-formulation for drug-resistant Cancer

MP More, SR Pardeshi, CV Pardeshi… - Medicine in Drug …, 2021 - Elsevier
The graph of drug resistance in cancer is reportedly increasing in terms of therapeutic
efficiency. As per the WHO reports, around 70% of death reported in low-and middle-income …

[HTML][HTML] Potential of Kalanchoe pinnata as a Cancer Treatment Adjuvant and an Epigenetic Regulator

ME Hernández-Caballero, JA Sierra-Ramírez… - Molecules, 2022 - mdpi.com
Cancer is a global public health problem that is related to different environmental and
lifestyle factors. Although the combination of screening, prevention, and treatment of cancer …

Layer-by-Layer assembled nano-drug delivery systems for cancer treatment

X Zhang, T Liang, Q Ma - Drug Delivery, 2021 - Taylor & Francis
Nano-drug delivery systems (NDDS) are functional drug-loaded nanocarriers widely applied
in cancer therapy. Recently, layer-by-layer (LbL) assembled NDDS have been …

Modulation of TLR/NF-κB/NLRP signaling by bioactive phytocompounds: A promising strategy to augment cancer chemotherapy and immunotherapy

S Fakhri, SZ Moradi, A Yarmohammadi… - Frontiers in …, 2022 - frontiersin.org
Background Tumors often progress to a more aggressive phenotype to resist drugs. Multiple
dysregulated pathways are behind this tumor behavior which is known as cancer …

Macrophage-membrane-camouflaged disintegrable and excretable nanoconstruct for deep tumor penetration

K Poudel, A Banstola, M Gautam, Z Soe… - … applied materials & …, 2020 - ACS Publications
The consolidation of nanovectors with biological membranes has recently been a subject of
interest owing to the prolonged systemic circulation time and delayed clearance by the …