Catheter-associated urinary tract infections: current challenges and future prospects

GT Werneburg - Research and reports in urology, 2022 - Taylor & Francis
Catheter-associated urinary tract infection (CAUTI) is the most common healthcare-
associated infection and cause of secondary bloodstream infections. Despite many …

Glycomimetics for the inhibition and modulation of lectins

S Leusmann, P Ménová, E Shanin, A Titz… - Chemical Society …, 2023 - pubs.rsc.org
Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

The type IX secretion system (T9SS): highlights and recent insights into its structure and function

AM Lasica, M Ksiazek, M Madej… - Frontiers in cellular and …, 2017 - frontiersin.org
Protein secretion systems are vital for prokaryotic life, as they enable bacteria to acquire
nutrients, communicate with other species, defend against biological and chemical agents …

A comprehensive guide to pilus biogenesis in Gram-negative bacteria

MK Hospenthal, TRD Costa, G Waksman - Nature reviews microbiology, 2017 - nature.com
Pili are crucial virulence factors for many Gram-negative pathogens. These surface
structures provide bacteria with a link to their external environments by enabling them to …

[HTML][HTML] Protein stability: a crystallographer's perspective

MC Deller, L Kong, B Rupp - Structural Biology and Crystallization …, 2016 - journals.iucr.org
Protein stability is a topic of major interest for the biotechnology, pharmaceutical and food
industries, in addition to being a daily consideration for academic researchers studying …

Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection

TJ Hannan, M Totsika, KJ Mansfield… - FEMS microbiology …, 2012 - academic.oup.com
Bladder infections affect millions of people yearly, and recurrent symptomatic infections
(cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …

Bacterial adhesins in host-microbe interactions

KA Kline, S Fälker, S Dahlberg, S Normark… - Cell host & …, 2009 - cell.com
Most commensal and pathogenic bacteria interacting with eukaryotic hosts express
adhesive molecules on their surfaces that promote interaction with host cell receptors or with …

Drug and vaccine development for the treatment and prevention of urinary tract infections

VP O'brien, TJ Hannan, HV Nielsen… - Urinary Tract Infections …, 2017 - Wiley Online Library
Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …

Structural basis for outer membrane lipopolysaccharide insertion

H Dong, Q **ang, Y Gu, Z Wang, NG Paterson… - Nature, 2014 - nature.com
Lipopolysaccharide (LPS) is essential for most Gram-negative bacteria and has crucial roles
in protection of the bacteria from harsh environments and toxic compounds, including …

Reaching the end of the line: urinary tract infections

KO Tamadonfar, NS Omattage… - Microbiology …, 2019 - journals.asm.org
Urinary tract infections (UTIs) cause a substantial health care burden. UTIs (i) are most often
caused by uropathogenic Escherichia coli (UPEC),(ii) primarily affect otherwise healthy …