Neuronal calcium signaling

MJ Berridge - Neuron, 1998 - cell.com
1962). Indeed, the two membranes are separated by a Calcium plays an important role in
regulating a great fuzzy material with a distinct periodicity reminiscent of variety of neuronal …

Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons

A Verkhratsky - Physiological reviews, 2005 - journals.physiology.org
The endoplasmic reticulum (ER) is the largest single intracellular organelle, which is present
in all types of nerve cells. The ER is an interconnected, internally continuous system of …

Calcium-induced calcium release in neurones

A Verkhratsky, A Shmigol - Cell calcium, 1996 - Elsevier
Neurones express several subtypes of intracellular Ca2+ channels, which are regulated by
cytoplasmic calcium concentration ([Ca2+] c) and provide the pathway for Ca2+-induced …

Ion channels in presynaptic nerve terminals and control of transmitter release

A Meir, S Ginsburg, A Butkevich… - Physiological …, 1999 - journals.physiology.org
The primary function of the presynaptic nerve terminal is to release transmitter quanta and
thus activate the postsynaptic target cell. In almost every step leading to the release of …

Intraluminal calcium as a primary regulator of endoplasmic reticulum function

D Burdakov, OH Petersen, A Verkhratsky - Cell calcium, 2005 - Elsevier
The concentration of Ca2+ inside the lumen of endoplasmic reticulum (ER) regulates a vast
array of spatiotemporally distinct cellular processes, from intracellular Ca2+ signals to intra …

Pharmacological regulation of endoplasmic reticulum structure and calcium dynamics: importance for neurodegenerative diseases

I Parkkinen, A Their, MY Asghar, S Sree… - Pharmacological …, 2023 - Elsevier
The endoplasmic reticulum (ER) is the largest organelle of the cell, composed of a
continuous network of sheets and tubules, and is involved in protein, calcium (Ca 2+), and …

The endoplasmic reticulum and neuronal calcium signalling

A Verkhratsky - Cell calcium, 2002 - Elsevier
The endoplasmic reticulum (ER) is a multifunctional signalling organelle regulating a wide
range of neuronal functional responses. The ER is intimately involved in intracellular Ca2+ …

Neuronal Ca2+-activated Cl− channels—homing in on an elusive channel species

S Frings, D Reuter, SJ Kleene - Progress in neurobiology, 2000 - Elsevier
Ca2+-activated Cl− channels control electrical excitability in various peripheral and central
populations of neurons. Ca2+ influx through voltage-gated or ligand-operated channels, as …

Release and sequestration of calcium by ryanodine‐sensitive stores in rat hippocampal neurones

O Garaschuk, Y Yaari, A Konnerth - The Journal of physiology, 1997 - Wiley Online Library
1 The properties of ryanodine‐sensitive Ca2+ stores in CA1 pyramidal cells were
investigated in rat hippocampal slices by using whole‐cell patch‐clamp recordings …

Endoplasmic reticulum Ca2+ homeostasis and neuronal death

A Verkhratsky, EC Toescu - Journal of cellular and molecular …, 2003 - Wiley Online Library
The endoplasmic reticulum (ER) is a universal signalling organelle, which regulates a wide
range of neuronal functional responses. Calcium release from the ER underlies various …