Gastropod immunobiology

ES Loker - Adv Exp Med Biol, 2010 - Springer
Over their 500 million year history, gastropods have radiated into marine, freshwater and
terrestrial environments and adopted life styles ranging from herbivory to carnivory to …

Treading the path towards genetic control of snail resistance to schistosome infection

DO Famakinde - Tropical medicine and infectious disease, 2018 - mdpi.com
Schistosomiasis remains the most important tropical snail-borne trematodiasis that threatens
many millions of human lives. In achieving schistosomiasis elimination targets, sustainable …

A somatically diversified defense factor, FREP3, is a determinant of snail resistance to schistosome infection

PC Hanington, MA Forys, ES Loker - PLoS neglected tropical …, 2012 - journals.plos.org
Schistosomiasis, a neglected tropical disease, owes its continued success to freshwater
snails that support production of prolific numbers of human-infective cercariae. Encounters …

Differential transcriptomic responses of Biomphalaria glabrata (Gastropoda, Mollusca) to bacteria and metazoan parasites, Schistosoma mansoni and Echinostoma …

CM Adema, PC Hanington, CM Lun… - Molecular …, 2010 - Elsevier
A 70-mer-oligonucleotide-based microarray (1152 features) that emphasizes stress and
immune responses factors was constructed to study transcriptomic responses of the snail …

Cypermethrin-induced nigrostriatal dopaminergic neurodegeneration alters the mitochondrial function: a proteomics study

S Agrawal, A Singh, P Tripathi, M Mishra… - Molecular …, 2015 - Springer
Cypermethrin induces the slow and progressive degeneration of the nigrostriatal
dopaminergic neurons in rats. Postnatal preexposure with low doses of cypermethrin is …

Single-cell RNA-seq profiling of individual Biomphalaria glabrata immune cells with a focus on immunologically relevant transcripts

H Li, AA Gharamah, JR Hambrook, X Wu… - Immunogenetics, 2022 - Springer
The immune cells of the snail Biomphalaria glabrata are classified into hyalinocyte and
granulocyte subtypes. Both subtypes are essential for the proper functioning of the snail …

Time series analysis of the transcriptional responses of Biomphalaria glabrata throughout the course of intramolluscan development of Schistosoma mansoni and …

PC Hanington, CM Lun, CM Adema… - International journal for …, 2010 - Elsevier
Successful colonization of a compatible snail host by a digenetic trematode miracidium
initiates a complex, proliferative development program requiring weeks to reach culmination …

A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products

K Li, S Zhao, J Long, J Su, L Wu, J Tao, J Zhou… - Cancer cell …, 2020 - Springer
Background Melanoma is one of the most aggressive tumors with the remarkable
characteristic of resistance to traditional chemotherapy and radiotherapy. Although targeted …

Reversing the Resistance Phenotype of the Biomphalaria glabrata Snail Host Schistosoma mansoni Infection by Temperature Modulation

W Ittiprasert, M Knight - PLoS pathogens, 2012 - journals.plos.org
Biomphalaria glabrata snails that display either resistant or susceptible phenotypes to the
parasitic trematode, Schistosoma mansoni provide an invaluable resource towards …

Resistance of Biomphalaria glabrata 13-16-R1 snails to Schistosoma mansoni PR1 is a function of haemocyte abundance and constitutive levels of specific transcripts …

MK Larson, RC Bender, CJ Bayne - International journal for parasitology, 2014 - Elsevier
Continuing transmission of human intestinal schistosomiasis depends on the parasite's
access to susceptible snail intermediate hosts (often Biomphalaria glabrata). Transmission …