The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …

Polyphenols, including phenolic acids, flavonoids, and procyanidins, are abundant in food
and beverage derived from plants. Tea (Camellia sinensis) is particularly rich in polyphenols …

Objective Non-alcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma
(HCC) is an increasing healthcare burden worldwide. We examined the role of dietary …

A high-fat diet (HFD) can easily induce obesity and change the gut microbiota and its
metabolites. However, studies on the effects of high-fat diets on the host have drawn …

Alterations in the gut microbiome, including diet-driven changes, are linked to the rising
prevalence of food allergy. However, little is known about how specific gut bacteria trigger …

Rationale: Several studies have suggested a role for the gut microbiota in inflammation and
atherogenesis. A causal relation relationship between gut microbiota, inflammation, and …

Intestinal inflammation shifts microbiota composition and metabolism. How the host monitors
and responds to such changes remains unclear. Here, we describe a protective mechanism …

The microbiota and the gastrointestinal mucus layer play a pivotal role in protection against
non-typhoidal Salmonella enterica serovar Typhimurium (S. Tm) colitis. Here, we analyzed …

Trillions of bacteria inhabit the mammalian gastrointestinal tract. In the majority of hosts,
these symbionts contribute largely to beneficial functions promoting microbe-host …

Exclusive enteral nutrition (EEN) with fiber-free diets is an effective steroid-sparing treatment
to induce clinical remission in children with Crohn's disease (CD). However, the mechanism …