Cell penetrating peptides, novel vectors for gene therapy

RE Taylor, M Zahid - Pharmaceutics, 2020 - mdpi.com
Cell penetrating peptides (CPPs), also known as protein transduction domains (PTDs), first
identified~ 25 years ago, are small, 6–30 amino acid long, synthetic, or naturally occurring …

Protein-based delivery systems for RNA delivery

H Zhu, H Luo, R Chang, Y Yang, D Liu, Y Ji… - Journal of Controlled …, 2023 - Elsevier
RNA-based therapeutics have emerged as promising approaches to modulate gene
expression and generate therapeutic proteins or antigens capable of inducing immune …

Machine-learning-based prediction of cell-penetrating peptides and their uptake efficiency with improved accuracy

B Manavalan, S Subramaniyam, TH Shin… - Journal of proteome …, 2018 - ACS Publications
Cell-penetrating peptides (CPPs) can enter cells as a variety of biologically active
conjugates and have various biomedical applications. To offset the cost and effort of …

Uptake pathways of cell-penetrating peptides in the context of drug delivery, gene therapy, and vaccine development

M Dowaidar - Cellular Signalling, 2024 - Elsevier
Cell-penetrating peptides have been extensively utilized for the purpose of facilitating the
intracellular delivery of cargo that is impermeable to the cell membrane. The researchers …

Biological membrane-penetrating peptides: computational prediction and applications

ECL de Oliveira, KS da Costa, PS Taube… - Frontiers in Cellular …, 2022 - frontiersin.org
Peptides comprise a versatile class of biomolecules that present a unique chemical space
with diverse physicochemical and structural properties. Some classes of peptides are able to …

Peptide-drug co-assembling: A potent armament against cancer

C Wu, M Wang, J Sun, Y Jia, X Zhu, G Liu, Y Zhu… - …, 2023 - pmc.ncbi.nlm.nih.gov
Cancer is still one of the major problems threatening human health and the therapeutical
efficacies of available treatment choices are often rather low. Due to their favorable …

Treatment of COVID‐19 patients with a SARS‐CoV‐2‐specific siRNA‐peptide dendrimer formulation

M Khaitov, A Nikonova, I Kofiadi, I Shilovskiy… - Allergy, 2023 - Wiley Online Library
Background Severe acute respiratory syndrome corona virus (SARS‐CoV‐2) infection
frequently causes severe and prolonged disease but only few specific treatments are …

[หนังสือ][B] CPP, cell-penetrating peptides

Ü Langel - 2019 - Springer
The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …

Peptide nanostructures-based delivery of DNA nanomaterial therapeutics for regulating gene expression

B Baral, B Panigrahi, A Kar, KD Tulsiyan… - … Therapy-Nucleic Acids, 2023 - cell.com
Self-assembled branched DNA (bDNA) nanomaterials have exhibited their functionality in
various biomedical and diagnostic applications. However, the anionic cellular membrane …

[HTML][HTML] Short Peptides as Powerful Arsenal for Smart Fighting Cancer

J Bojarska, WM Wolf - Cancers, 2024 - mdpi.com
Simple Summary This mini-review summarizes the up-to-date progress in develo**
anticancer therapies based on cutting-edge strategies employing short peptides. This work …