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The Keap1‐Nrf2 system: a mediator between oxidative stress and aging
C Yu, JH **ao - Oxidative Medicine and Cellular Longevity, 2021 - Wiley Online Library
Oxidative stress, a term that describes the imbalance between oxidants and antioxidants,
leads to the disruption of redox signals and causes molecular damage. Increased oxidative …
leads to the disruption of redox signals and causes molecular damage. Increased oxidative …
[HTML][HTML] Glycogen synthase kinase-3 signaling in Alzheimer's disease
E Lauretti, O Dincer, D Praticò - … et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common form of neurodegenerative disorder with
dementia, accounting for approximately 70% of the all cases. Currently, 5.8 million people in …
dementia, accounting for approximately 70% of the all cases. Currently, 5.8 million people in …
GSK-3 and Tau: a key duet in Alzheimer's disease
CL Sayas, J Ávila - Cells, 2021 - mdpi.com
Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase
with a plethora of substrates. As a modulator of several cellular processes, GSK-3 has a …
with a plethora of substrates. As a modulator of several cellular processes, GSK-3 has a …
α-synuclein in the pathophysiology of Alzheimer's disease
D Twohig, HM Nielsen - Molecular neurodegeneration, 2019 - Springer
The Alzheimer's disease (AD) afflicted brain is neuropathologically defined by extracellular
amyloid-β (Aβ) plaques and intraneuronal neurofibrillary tangles composed of …
amyloid-β (Aβ) plaques and intraneuronal neurofibrillary tangles composed of …
[HTML][HTML] GSK-3β in DNA repair, apoptosis, and resistance of chemotherapy, radiotherapy of cancer
J Lin, T Song, C Li, W Mao - … et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Glycogen synthase kinase-3β (GSK-3β) is an evolutionarily conserved serine/threonine
kinase, functioning in numerous cellular processes including cell proliferation, DNA repair …
kinase, functioning in numerous cellular processes including cell proliferation, DNA repair …
Dopamine receptors–IUPHAR R eview 13
The variety of physiological functions controlled by dopamine in the brain and periphery is
mediated by the D 1, D 2, D 3, D 4 and D 5 dopamine GPCRs. Drugs acting on dopamine …
mediated by the D 1, D 2, D 3, D 4 and D 5 dopamine GPCRs. Drugs acting on dopamine …
Glycogen synthesis and beyond, a comprehensive review of GSK3 as a key regulator of metabolic pathways and a therapeutic target for treating metabolic diseases
L Wang, J Li, L Di - Medicinal Research Reviews, 2022 - Wiley Online Library
Abstract Glycogen synthase kinase‐3 (GSK3) is a highly evolutionarily conserved
serine/threonine protein kinase first identified as an enzyme that regulates glycogen …
serine/threonine protein kinase first identified as an enzyme that regulates glycogen …
The β-catenin destruction complex
JL Stamos, WI Weis - Cold Spring Harbor perspectives …, 2013 - cshperspectives.cshlp.org
The Wnt/β-catenin pathway is highly regulated to insure the correct temporal and spatial
activation of its target genes. In the absence of a Wnt stimulus, the transcriptional coactivator …
activation of its target genes. In the absence of a Wnt stimulus, the transcriptional coactivator …
Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium
The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …
investigation of coordination and organometallic complexes of alternative metal centers for …
Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link
Y Zhang, N Huang, F Yan, H **, S Zhou, J Shi… - Behavioural brain …, 2018 - Elsevier
It is well known that Alzheimer's disease (AD) is closely related to diabetes mellitus (DM),
and AD is also regarded as Type 3 diabetes (T3D). However, the exact link between AD and …
and AD is also regarded as Type 3 diabetes (T3D). However, the exact link between AD and …