As the most common chronic degenerative joint disease, osteoarthritis (OA) is the leading
cause of pain and physical disability, affecting millions of people worldwide. Mainly …

In diarthrodial joints, the articular cartilage, calcified cartilage, and subchondral cortical and
trabecular bone form a biocomposite—referred to as the osteochondral unit—that is …

Osteoarthritis (OA) is one of the most commonly occurring forms of arthritis in the world
today. It is a debilitating chronic illness causing pain and immense discomfort to the affected …

Osteoarthritis (OA) is the most common joint disorder, is associated with an increasing
socioeconomic impact owing to the ageing population and mainly affects the diarthrodial …

The progression of osteoarthritis is associated with inflammation triggered by the enzymatic
degradation of extracellular matrix in injured cartilage. Here we show that a locally injected …

Osteoarthritis (OA) is a progressive and disabling musculoskeletal disease affecting millions
of people and resulting in major healthcare costs worldwide. It is the most common form of …

OBJECTIVE: Post-traumatic osteoarthritis (PTOA) is a common consequence of traumatic
joint injury, with 50% of anterior cruciate ligament (ACL) rupture patients develo** PTOA …

For patients presenting knee pain coming from osteoarthritis (OA), non-pharmacological
conservative treatments (eg, physical therapy interventions) are among the first methods in …

Objective Alterations in the mechanical loading environment in joints may have both
beneficial and detrimental effects on articular cartilage and subchondral bone, and may …

Osteoarthritis (OA) is a prevalent, disabling disorder of the joints that affects a large
population worldwide and for which there is no definitive cure. This review provides critical …