The inositol trisphosphate/calcium signaling pathway in health and disease
MJ Berridge - Physiological reviews, 2016 - journals.physiology.org
Many cellular functions are regulated by calcium (Ca2+) signals that are generated by
different signaling pathways. One of these is the inositol 1, 4, 5-trisphosphate/calcium …
different signaling pathways. One of these is the inositol 1, 4, 5-trisphosphate/calcium …
Inositol Trisphosphate Receptor Ca2+ Release Channels
The inositol 1, 4, 5-trisphosphate (InsP3) receptors (InsP3Rs) are a family of Ca2+ release
channels localized predominately in the endoplasmic reticulum of all cell types. They …
channels localized predominately in the endoplasmic reticulum of all cell types. They …
Microdomains of Intracellular Ca2+: Molecular Determinants and Functional Consequences
Calcium ions are ubiquitous and versatile signaling molecules, capable of decoding a
variety of extracellular stimuli (hormones, neurotransmitters, growth factors, etc.) into …
variety of extracellular stimuli (hormones, neurotransmitters, growth factors, etc.) into …
Mitochondrial calcium: effects of its imbalance in disease
D Matuz-Mares, M González-Andrade… - Antioxidants, 2022 - mdpi.com
Calcium is used in many cellular processes and is maintained within the cell as free calcium
at low concentrations (approximately 100 nM), compared with extracellular (millimolar) …
at low concentrations (approximately 100 nM), compared with extracellular (millimolar) …
Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration
The endoplasmic reticulum (ER) is a dynamic intracellular organelle with multiple functions
essential for cellular homeostasis, development, and stress responsiveness. In response to …
essential for cellular homeostasis, development, and stress responsiveness. In response to …
[HTML][HTML] Smooth muscle ion channels and regulation of vascular tone in resistance arteries and arterioles
Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
M Høyer-Hansen, M Jäättelä - Cell Death & Differentiation, 2007 - nature.com
Eukaryotic cells respond to the accumulation of unfolded proteins in the endoplasmic
reticulum (ER) either by unfolded protein response that leads to an increase in the capacity …
reticulum (ER) either by unfolded protein response that leads to an increase in the capacity …
Calcium flickers steer cell migration
Well-organized calcium signal in space, time and concentration is essential to directional
movement, which is common to all cell types during development and critical to tissue …
movement, which is common to all cell types during development and critical to tissue …
The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control
A Görlach, P Klappa, DT Kietzmann - Antioxidants & redox signaling, 2006 - liebertpub.com
The endoplasmic reticulum (ER) plays a major role in regulating synthesis, folding, and
orderly transport of proteins. It is also essentially involved in various cellular signaling …
orderly transport of proteins. It is also essentially involved in various cellular signaling …
The structural basis of ryanodine receptor ion channel function
G Meissner - Journal of General Physiology, 2017 - rupress.org
Large-conductance Ca2+ release channels known as ryanodine receptors (RyRs) mediate
the release of Ca2+ from an intracellular membrane compartment, the endo/sarcoplasmic …
the release of Ca2+ from an intracellular membrane compartment, the endo/sarcoplasmic …