Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Contrast-enhanced magnetic resonance imaging (MRI) is an indispensable tool for
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …

Cancer cells are characterized by a metabolic shift in cellular energy production,
orchestrated by the transcription factor HIF-1α, from mitochondrial oxidative phosphorylation …

Non-invasive imaging methods for detecting intratumoural viral spread and host responses
to oncolytic virotherapy are either slow, lack specificity or require the use of radioactive or …

Gd-based MRI contrast agents (GBCAs) have come under intense regulatory scrutiny due to
concerns of Gd retention and delayed toxicity. Three GBCAs comprising acyclic Gd chelates …

Background Tumour acidosis is considered to play a central role in promoting cancer
invasion and migration, but few studies have investigated in vivo how tumour pH correlates …

Purpose To develop an automated machine‐learning‐based method for the discovery of
rapid and quantitative chemical exchange saturation transfer (CEST) MR fingerprinting …

Image guided nose-to-brain drug delivery provides a non-invasive way to monitor drug
delivered to the brain, and the intranasal administration could increase effective dose via …

Immunotherapy constitutes a paradigm shift in cancer treatment. Its FDA approval for several
indications has yielded improved prognosis for cases where traditional therapy has shown …

Altered metabolism is considered a core hallmark of cancer. By monitoring in vivo
metabolites changes or characterizing the tumor microenvironment, non-invasive imaging …