Migraine is an extremely disabling, common neurological disorder characterized by a
complex neurobiology, involving a series of central and peripheral nervous system areas …

Background In individuals with migraine, attacks may increase in frequency, severity, or
both. Preventing migraine progression has emerged as a treatment goal in headache …

Objective To incorporate recent research findings, expert consensus, and patient
perspectives into updated guidance on the use of new acute and preventive treatments for …

Brain diseases, including neurodegenerative, cerebrovascular and neuropsychiatric
diseases, have posed a deleterious threat to human health and brought a great burden to …

Vagus nerve stimulation (VNS) is a technology that provides electrical stimulation to the
cervical vagus nerve and can be applied in the treatment of a wide variety of …

The role of the trigeminal system in facial and dural sensitivity has been recognized for a
long time. More recently, the trigeminal system has also been considered a prominent actor …

Objective To assess the efficacy and safety of a remote electrical neuromodulation (REN)
device for the acute treatment of migraine. Background There is a significant unmet need for …

Stroke is a leading cause of disability worldwide, and in approximately 60% of individuals,
upper limb deficits persist 6 months after stroke. These deficits adversely affect the functional …

Objective To outline strategies for the treatment of migraine which do not require in‐person
visits to clinic or the emergency department, and to describe ways that health insurance …

Importance Migraine is common and can be associated with significant morbidity, and
several treatment options exist for acute therapy. Objective To evaluate the benefits and …