Hypoxia-induced signaling in the cardiovascular system: pathogenesis and therapeutic targets

Y Zhao, W ** post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis
I Godet, YJ Shin, JA Ju, IC Ye, G Wang… - Nature …, 2019 - nature.com
Hypoxia is known to be detrimental in cancer and contributes to its development. In this
work, we present an approach to fate-map hypoxic cells in vivo in order to determine their …

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

B Keith, RS Johnson, MC Simon - Nature Reviews Cancer, 2012 - nature.com
Hypoxia-inducible factors (HIFs) are broadly expressed in human cancers, and HIF1α and
HIF2α were previously suspected to promote tumour progression through largely …

[HTML][HTML] Novel drugs with high efficacy against tumor angiogenesis

S Qi, S Deng, Z Lian, K Yu - International Journal of Molecular Sciences, 2022 - mdpi.com
Angiogenesis is involved in physiological and pathological processes in the body. Tumor
angiogenesis is a key factor associated with tumor growth, progression, and metastasis …