An update on oxidative damage to spermatozoa and oocytes

CS Opuwari, RR Henkel - BioMed research international, 2016 - Wiley Online Library
On the one hand, reactive oxygen species (ROS) are mandatory mediators for essential
cellular functions including the function of germ cells (oocytes and spermatozoa) and …

Sperm preparation: state-of-the-art—physiological aspects and application of advanced sperm preparation methods

R Henkel - Asian journal of andrology, 2011 - pmc.ncbi.nlm.nih.gov
For assisted reproduction technologies (ART), numerous techniques were developed to
isolate spermatozoa capable of fertilizing oocytes. While early methodologies only focused …

Glycodelin-A stimulates the conversion of human peripheral blood CD16CD56bright NK cell to a decidual NK cell-like phenotype

CL Lee, M Vijayan, X Wang, KKW Lam… - Human …, 2019 - academic.oup.com
Abstract STUDY QUESTION Does glycodelin-A (GdA) induce conversion of human
peripheral blood CD16− CD56bright natural killer (NK) cells to decidual NK (dNK) cells to …

The potential role of seminal plasma in the fertilization outcomes

J Szczykutowicz, A Kałuża… - BioMed research …, 2019 - Wiley Online Library
For human infertility both male and female factors may be equally important. Searching for
molecular biomarkers of male infertility, neglected for decades, and the attempts to explain …

Proteomic and functional analysis of human sperm detergent resistant membranes

B Nixon, LA Mitchell, AL Anderson… - Journal of cellular …, 2011 - Wiley Online Library
Mammalian spermatozoa attain the ability to fertilize an oocyte as they negotiate the female
reproductive tract. This acquisition of functional competence is preceded by an intricate …

Glycan evolution in response to collaboration, conflict, and constraint

SA Springer, P Gagneux - Journal of Biological Chemistry, 2013 - jbc.org
Glycans, oligo-and polysaccharides secreted or attached to proteins and lipids, cover the
surfaces of all cells and have a regulatory capacity and structural diversity beyond any other …

Biological functions and large-scale profiling of protein glycosylation in human semen

R Lan, M **n, Z Hao, S You, Y Xu, J Wu… - Journal of proteome …, 2020 - ACS Publications
Glycosylation is one of the most important post-translational modifications of proteins and
plays an essential role in spermatogenesis, maturation, extracellular quality control …

The pleiotropic effect of glycodelin‐A in early pregnancy

CL Lee, KKW Lam, M Vijayan… - American Journal of …, 2016 - Wiley Online Library
Successful pregnancy depends largely on adequate placentation and maternal tolerance of
the fetus. Glycodelin‐A is a glycoprotein abundant in the decidua during early pregnancy. It …

Sialylation: fate decision of mammalian sperm development, fertilization, and male fertility

S Yi, Y Feng, Y Wang, F Ma - Biology of Reproduction, 2023 - academic.oup.com
Sperm development, maturation, and successful fertilization within the female reproductive
tract are intricate and orderly processes that involve protein translation and post …

Glycodelin-A as a paracrine regulator in early pregnancy

CL Lee, KKW Lam, H Koistinen, M Seppala… - Journal of reproductive …, 2011 - Elsevier
Glycodelin-A (GdA) is a glycoprotein secreted from the endometrial glands and decidual
glandular epithelium. Given its abundance and ubiquitous distribution in the first trimester …