Cultured meat is a bearer of hope for sustainable meat production, aiming at ensuring global
food security while preserving environmental resources. Being a nascent industry, there are …

Cultured meat is an emerging biotechnology that aims to produce meat from animal cell
culture, rather than from the raising and slaughtering of livestock, on environmental and …

With the increasing global demand for meat, cultured meat technologies are emerging,
offering more sustainable solutions that aim to evade a future shortage of meat. Here, we …

The low bone marrow (BM) MSC titers demand a fast ex vivo expansion process to meet the
clinically relevant cell dosage. Attending to the low oxygen tension of BM in vivo, we studied …

The immunomodulatory properties of mesenchymal stem cells (MSCs) make them attractive
therapeutic agents for a wide range of diseases. However, the highly demanding cell doses …

Following cultivation of distinct mesenchymal stem cell (MSC) populations derived from
human umbilical cord under hypoxic conditions (between 1.5% to 5% oxygen (O 2)) …

For the first time, fully functional human mesenchymal stem cells (hMSCs) have been
cultured at the litre-scale on microcarriers in a stirred-tank 5 l bioreactor,(2.5 l working …

Spheroids formed of mesenchymal stem cells (MSCs) exhibit increased cell survival and
trophic factor secretion compared with dissociated MSCs, making them therapeutically …

The large cell doses (> 1× 106 cells/kg) used in clinical trials with mesenchymal
stem/stromal cells (MSC) will require an efficient production process. Moreover, monitoring …

Bioreactor systems have been developed as alternatives to standard culture flasks due to
their homogeneous nature, easiness of monitoring and increased cell production. Here we …