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Sha** the brain vasculature in development and disease in the single-cell era
The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …
Genetic basis and therapies for vascular anomalies
Vascular and lymphatic malformations represent a challenge for clinicians. The identification
of inherited and somatic mutations in important signaling pathways, including the PI3K …
of inherited and somatic mutations in important signaling pathways, including the PI3K …
Vascular anomalies classification: recommendations from the International Society for the Study of Vascular Anomalies
M Wassef, F Blei, D Adams, A Alomari, E Baselga… - …, 2015 - publications.aap.org
Vascular anomalies represent a spectrum of disorders from a simple “birthmark” to life-
threatening entities. Incorrect nomenclature and misdiagnoses are commonly experienced …
threatening entities. Incorrect nomenclature and misdiagnoses are commonly experienced …
Lymphatic system in cardiovascular medicine
The mammalian circulatory system comprises both the cardiovascular system and the
lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a …
lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a …
Childhood stroke
Stroke is an important cause of neurological morbidity in children; most survivors have
permanent neurological deficits that affect the remainder of their life. Stroke in childhood, the …
permanent neurological deficits that affect the remainder of their life. Stroke in childhood, the …
Recent advances in RASopathies
RASopathies or RAS/mitogen-activated protein kinase (MAPK) syndromes are a group of
phenotypically overlap** syndromes caused by germline mutations that encode …
phenotypically overlap** syndromes caused by germline mutations that encode …
Germline loss-of-function mutations in EPHB4 cause a second form of capillary malformation-arteriovenous malformation (CM-AVM2) deregulating RAS-MAPK …
Background: Most arteriovenous malformations (AVMs) are localized and occur
sporadically. However, they also can be multifocal in autosomal-dominant disorders, such …
sporadically. However, they also can be multifocal in autosomal-dominant disorders, such …
Hereditary hemorrhagic telangiectasia: genetics and molecular diagnostics in a new era
J McDonald, W Wooderchak-Donahue… - Frontiers in …, 2015 - frontiersin.org
Hereditary hemorrhagic telangiectasia (HHT) is a vascular dysplasia characterized by
telangiectases and arteriovenous malformations (AVMs) in particular locations described in …
telangiectases and arteriovenous malformations (AVMs) in particular locations described in …
Genetics of lymphatic anomalies
Lymphatic anomalies include a variety of developmental and/or functional defects affecting
the lymphatic vessels: sporadic and familial forms of primary lymphedema, secondary …
the lymphatic vessels: sporadic and familial forms of primary lymphedema, secondary …
[PDF][PDF] Central conducting lymphatic anomaly: from bench to bedside
Central conducting lymphatic anomaly (CCLA) is a complex lymphatic anomaly
characterized by abnormalities of the central lymphatics and may present with nonimmune …
characterized by abnormalities of the central lymphatics and may present with nonimmune …