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Efavirenz and the CNS: what we already know and questions that need to be answered
N Apostolova, HA Funes, A Blas-Garcia… - Journal of …, 2015 - academic.oup.com
The NNRTI efavirenz has long been one of the most frequently employed antiretroviral drugs
in the multidrug regimens used to treat HIV infection, in accordance with its well …
in the multidrug regimens used to treat HIV infection, in accordance with its well …
Mechanisms of action and persistent neuroplasticity by drugs of abuse
ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - Elsevier
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …
important for the homeostasis of brain processes and for learning and remembering …
Efavirenz: history, development and future
B Costa, N Vale - Biomolecules, 2022 - mdpi.com
Efavirenz (Sustiva®) is a first-generation non-nucleoside reverse transcriptase inhibitor
(NNRTI) used to treat human immunodeficiency virus (HIV) type 1 infection or to prevent the …
(NNRTI) used to treat human immunodeficiency virus (HIV) type 1 infection or to prevent the …
Mental health of quarantine and isolation
D Huremović - Psychiatry of pandemics: A mental health response to …, 2019 - Springer
Isolating exposed individuals from the unexposed ones is a crucial measure in breaking up
a chain of infection. All forms of separation and isolation, however, tend to impose an …
a chain of infection. All forms of separation and isolation, however, tend to impose an …
Adverse neuropsychiatric events and recreational use of efavirenz and other HIV-1 antiretroviral drugs
Efavirenz is a highly effective HIV-1 antiretroviral; however, it is also frequently associated
with neuropsychiatric adverse events (NPAE) that include abnormal dreams, sleep …
with neuropsychiatric adverse events (NPAE) that include abnormal dreams, sleep …
[HTML][HTML] HIV-associated apathy/depression and neurocognitive impairments reflect persistent dopamine deficits
Individuals living with human immunodeficiency virus type 1 (HIV-1) are often plagued by
debilitating neurocognitive impairments and affective alterations; the pathophysiology …
debilitating neurocognitive impairments and affective alterations; the pathophysiology …
Neuropsychiatric effects of HIV antiviral medications
GJ Treisman, O Soudry - Drug safety, 2016 - Springer
The development of antiretroviral therapy (ART) has dramatically increased the lifespan of
HIV patients but treatment is complicated by numerous adverse effects and toxicities. ART …
HIV patients but treatment is complicated by numerous adverse effects and toxicities. ART …
Evaluating neurodevelopmental consequences of perinatal exposure to antiretroviral drugs: current challenges and new approaches
As antiretroviral therapy (ART) becomes increasingly affordable and accessible to women of
childbearing age across the globe, the number of children who are exposed to Human …
childbearing age across the globe, the number of children who are exposed to Human …
Whoonga: Potential Recreational Use of HIV Antiretroviral Medication in South Africa
DJ Grelotti, EF Closson, JA Smit, Z Mabude… - AIDS and Behavior, 2014 - Springer
Whoonga is a drug cocktail in South Africa rumored to contain illicit drugs and HIV
antiretroviral (ARV) medication. Although its use may adversely impact adherence to HIV …
antiretroviral (ARV) medication. Although its use may adversely impact adherence to HIV …
HIV neuropathogenesis in the presence of a disrupted dopamine system
EA Nickoloff-Bybel, TM Calderon, PJ Gaskill… - Journal of Neuroimmune …, 2020 - Springer
Antiretroviral therapy (ART) has transformed HIV into a chronic condition, lengthening and
improving the lives of individuals living with this virus. Despite successful suppression of HIV …
improving the lives of individuals living with this virus. Despite successful suppression of HIV …