Define cancer-associated fibroblasts (CAFs) in the tumor microenvironment: new opportunities in cancer immunotherapy and advances in clinical trials
H Zhang, X Yue, Z Chen, C Liu, W Wu, N Zhang, Z Liu… - Molecular Cancer, 2023 - Springer
Despite centuries since the discovery and study of cancer, cancer is still a lethal and
intractable health issue worldwide. Cancer-associated fibroblasts (CAFs) have gained much …
intractable health issue worldwide. Cancer-associated fibroblasts (CAFs) have gained much …
Exosomes and cancer-Diagnostic and prognostic biomarkers and therapeutic vehicle
X Wang, L Tian, J Lu, IOL Ng - Oncogenesis, 2022 - nature.com
Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …
multistep endocytosis process and carry diverse functional molecular cargoes, including …
mRNA-based vaccines and therapeutics for COVID-19 and future pandemics
An unheard mobilization of resources to find SARS-CoV-2 vaccines and therapies has been
sparked by the COVID-19 pandemic. Two years ago, COVID-19's launch propelled mRNA …
sparked by the COVID-19 pandemic. Two years ago, COVID-19's launch propelled mRNA …
Exosome for mRNA delivery: strategies and therapeutic applications
Messenger RNA (mRNA) has emerged as a promising therapeutic molecule with numerous
clinical applications in treating central nervous system disorders, tumors, COVID-19, and …
clinical applications in treating central nervous system disorders, tumors, COVID-19, and …
Antitumor applications of photothermal agents and photothermal synergistic therapies
C Li, Y Cheng, D Li, Q An, W Zhang, Y Zhang… - International Journal of …, 2022 - mdpi.com
As a new tumor treatment strategy, photothermal therapy (PTT) has the advantages of
accuracy, ease of administration, a high efficiency and low side effects. Photothermal …
accuracy, ease of administration, a high efficiency and low side effects. Photothermal …
tRNA therapeutics for genetic diseases
Transfer RNAs (tRNAs) have a crucial role in protein synthesis, and in recent years, their
therapeutic potential for the treatment of genetic diseases—primarily those associated with a …
therapeutic potential for the treatment of genetic diseases—primarily those associated with a …
Utilizing non-coding RNA-mediated regulation of ATP binding cassette (ABC) transporters to overcome multidrug resistance to cancer chemotherapy
KKW To, Z Huang, H Zhang, CR Ashby Jr, L Fu - Drug Resistance Updates, 2024 - Elsevier
Multidrug resistance (MDR) is one of the primary factors that produces treatment failure in
patients receiving cancer chemotherapy. MDR is a complex multifactorial phenomenon …
patients receiving cancer chemotherapy. MDR is a complex multifactorial phenomenon …
Tumor-targeted exosomes for delivery of anticancer drugs
Exosomes are small phospholipid bilayer vesicles that are naturally produced by all living
cells, both prokaryotes and eukaryotes. The exosomes due to their unique size, reduced …
cells, both prokaryotes and eukaryotes. The exosomes due to their unique size, reduced …
Advances in lipid-based carriers for cancer therapeutics: Liposomes, exosomes and hybrid exosomes
Cancer has recently surpassed heart disease as the leading cause of deaths worldwide for
the age group 45–65 and has been the primary focus for biomedical researchers. Presently …
the age group 45–65 and has been the primary focus for biomedical researchers. Presently …
Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application
Q Yang, S Li, H Ou, Y Zhang, G Zhu, S Li… - Journal of …, 2024 - Springer
Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …