Many aspects of health and disease are modeled using the abstraction of a" pathway"—a
set of protein or other subcellular activities with specified functional linkages between them …

Neuronal networks are the standard heuristic model today for describing brain activity
associated with animal behavior. Recent studies have revealed an extensive role for a …

Metabolic reprogramming is a general feature of cancer cells. Regrettably, the
comprehensive quantification of metabolites in biological specimens does not promptly …

A well‐known hypothesis, with far‐reaching implications, is that biological evolution should
preferentially lead to states that are dynamically critical. In previous papers, we showed that …

Colon rectal cancers (CRC) are the result of sequences of mutations which lead the
intestinal tissue to develop in a carcinoma following a “progression” of observable …

Angiogenesis plays a key role in tumor growth and cancer progression. TIE-2-expressing
monocytes (TEM) have been reported to critically account for tumor vascularization and …

The number of mathematical models for biological pathways is rapidly growing. In particular,
Boolean modelling proved to be suited to describe large cellular signalling networks …

This review article focuses on studying problems of observability and controllability of
cellular automata (CAs) considered in the context of control theory, an important feature of …

Colorectal tumors originate and develop within intestinal crypts. Even though some of the
essential phenomena that characterize crypt structure and dynamics have been effectively …

We study the problem of master-slave synchronization and control of totalistic cellular
automata. The synchronization mechanism is that of setting a fraction of sites of the slave …