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High drug-loading nanomedicines: progress, current status, and prospects
S Shen, Y Wu, Y Liu, D Wu - International journal of nanomedicine, 2017 - Taylor & Francis
Drug molecules transformed into nanoparticles or endowed with nanostructures with or
without the aid of carrier materials are referred to as “nanomedicines” and can overcome …
without the aid of carrier materials are referred to as “nanomedicines” and can overcome …
Polymer nanomedicines
Polymer nanomedicines (macromolecular therapeutics, polymer-drug conjugates, drug-free
macromolecular therapeutics) are a group of biologically active compounds that are …
macromolecular therapeutics) are a group of biologically active compounds that are …
Nano‐star‐shaped polymers for drug delivery applications
With the advancement of polymer engineering, complex star‐shaped polymer architectures
can be synthesized with ease, bringing about a host of unique properties and applications …
can be synthesized with ease, bringing about a host of unique properties and applications …
Fluorescence optical imaging in anticancer drug delivery
In the past several decades, nanosized drug delivery systems with various targeting
functions and controlled drug release capabilities inside targeted tissues or cells have been …
functions and controlled drug release capabilities inside targeted tissues or cells have been …
Prodrugs for targeted cancer therapy
Introduction: Prodrugs have been used to improve the selectivity and efficacy of cancer
therapy by targeting unique abnormal markers that are overexpressed by cancer cells and …
therapy by targeting unique abnormal markers that are overexpressed by cancer cells and …
The light at the end of the tunnel—second generation HPMA conjugates for cancer treatment
It is almost four decades since N-(2-hydroxypropyl) methacrylamide (HPMA)-based
copolymers arose as drug carriers. Although fundamentals have been established and …
copolymers arose as drug carriers. Although fundamentals have been established and …
Strategies to prepare polymers with cleavable linkages releasing active agents in acidic media
Incorporating labile bonds in chemical structure of polymer yields interesting materials that
are responsive to change of environmental stimuli such as change of pH values. Active …
are responsive to change of environmental stimuli such as change of pH values. Active …
[HTML][HTML] Dendrimer prodrugs
The main objective of this review is to describe the importance of dendrimer prodrugs in the
design of new drugs, presenting numerous applications of these nanocomposites in the …
design of new drugs, presenting numerous applications of these nanocomposites in the …
Current trends in the development of HPMA-based block copolymeric nanoparticles for their application in drug delivery
Abstract N-(2-hydroxypropyl) methacrylamide-based block copolymers (pHPMA) have
received attention due to their hydrophilicity, non-immunogenicity, biocompatibility and …
received attention due to their hydrophilicity, non-immunogenicity, biocompatibility and …
[HTML][HTML] Fluorescence imaging as a tool in preclinical evaluation of polymer-based nano-DDS systems intended for cancer treatment
Targeted drug delivery using nano-sized carrier systems with targeting functions to
malignant and inflammatory tissue and tailored controlled drug release inside targeted …
malignant and inflammatory tissue and tailored controlled drug release inside targeted …