[HTML][HTML] Applications and limitations of dendrimers in biomedicine

AA Chis, C Dobrea, C Morgovan, AM Arseniu, LL Rus… - Molecules, 2020 - mdpi.com
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance

MA Iqbal, S Arora, G Prakasam, GA Calin… - Molecular aspects of …, 2019 - Elsevier
Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of
therapy throughout the world. Clinical success of therapies is not very promising due to-late …

Tumor microenvironment targeted nanotherapeutics for cancer therapy and diagnosis: A review

S Thakkar, D Sharma, K Kalia, RK Tekade - Acta biomaterialia, 2020 - Elsevier
Recent findings suggest that the cellular and extracellular materials surrounding the
cancerous cells from an atypical tumor microenvironment (TM) play a pivotal role in the …

Polymeric nanoparticles for targeted treatment in oncology: current insights

RH Prabhu, VB Patravale, MD Joshi - International journal of …, 2015 - Taylor & Francis
Chemotherapy, a major strategy for cancer treatment, lacks the specificity to localize the
cancer therapeutics in the tumor site, thereby affecting normal healthy tissues and …

Viral and nonviral delivery systems for gene delivery

N Nayerossadat, T Maedeh, PA Ali - Advanced biomedical …, 2012 - journals.lww.com
Gene therapy is the process of introducing foreign genomic materials into host cells to elicit
a therapeutic benefit. Although initially the main focus of gene therapy was on special …

Silk fibroin nanoparticle as a novel drug delivery system

F Mottaghitalab, M Farokhi, MA Shokrgozar… - Journal of Controlled …, 2015 - Elsevier
Abstract Design and synthesis of efficient drug delivery systems are of vital importance for
medicine and healthcare. Nanocarrier-based drug delivery systems, in particular …

Targeting and delivery of platinum-based anticancer drugs

X Wang, Z Guo - Chemical Society Reviews, 2013 - pubs.rsc.org
Platinum-based anticancer drugs occupy a crucial role in the treatment of various malignant
tumours. However, the efficacy and applicability of platinum drugs are heavily restricted by …

Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics …

D Astruc, E Boisselier, C Ornelas - Chemical reviews, 2010 - ACS Publications
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular
Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and …

Cancer nanotechnology: application of nanotechnology in cancer therapy

R Misra, S Acharya, SK Sahoo - Drug discovery today, 2010 - Elsevier
The application of nanotechnology for cancer therapy has received considerable attention in
recent years. Cancer nanotechnology (an interdisciplinary area of research in science …

Targeting nanoparticles to cancer

M Wang, M Thanou - Pharmacological research, 2010 - Elsevier
Nanotechnology applications in medicine, termed as nanomedicine, have introduced a
number of nanoparticles of variable chemistry and architecture for cancer imaging and …