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Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications
The induced pluripotent stem cell (iPSC) technology has transformed in vitro research and
holds great promise to advance regenerative medicine. iPSCs have the capacity for an …
holds great promise to advance regenerative medicine. iPSCs have the capacity for an …
[HTML][HTML] AI-enabled organoids: construction, analysis, and application
L Bai, Y Wu, G Li, W Zhang, H Zhang, J Su - Bioactive materials, 2024 - Elsevier
Organoids, miniature and simplified in vitro model systems that mimic the structure and
function of organs, have attracted considerable interest due to their promising applications in …
function of organs, have attracted considerable interest due to their promising applications in …
BANKSY unifies cell ty** and tissue domain segmentation for scalable spatial omics data analysis
Spatial omics data are clustered to define both cell types and tissue domains. We present
Building Aggregates with a Neighborhood Kernel and Spatial Yardstick (BANKSY), an …
Building Aggregates with a Neighborhood Kernel and Spatial Yardstick (BANKSY), an …
Sulfur fluoride exchange
Click chemistry is a conceptual strategy to rapidly synthesize and discover functional
molecules. Sulfur fluoride exchange (SuFEx) is a click reaction that has revolutionized …
molecules. Sulfur fluoride exchange (SuFEx) is a click reaction that has revolutionized …
Heterogeneity of hepatocellular carcinoma: from mechanisms to clinical implications
Hepatocellular Carcinoma (HCC) is one of the most common types of primary liver cancer.
Current treatment options have limited efficacy against this malignancy, primarily owing to …
Current treatment options have limited efficacy against this malignancy, primarily owing to …
Generating human bone marrow organoids for disease modeling and drug discovery
AA Olijnik, A Rodriguez-Romera, ZC Wong, Y Shen… - Nature protocols, 2024 - nature.com
The bone marrow supports and regulates hematopoiesis, responding to physiological
requirements for blood cell production over ontogeny and during pathological challenges …
requirements for blood cell production over ontogeny and during pathological challenges …
Advanced 3D imaging and organoid bioprinting for biomedical research and therapeutic applications
Organoid cultures offer a valuable platform for studying organ-level biology, allowing for a
closer mimicry of human physiology compared to traditional two-dimensional cell culture …
closer mimicry of human physiology compared to traditional two-dimensional cell culture …
[HTML][HTML] An overview of in vitro 3D models of the blood-brain barrier as a tool to predict the in vivo permeability of nanomedicines
The blood–brain barrier (BBB) prevents efficient drug delivery to the central nervous system.
As a result, brain diseases remain one of the greatest unmet medical needs. Understanding …
As a result, brain diseases remain one of the greatest unmet medical needs. Understanding …
A beginner's guide to cell culture: Practical advice for preventing needless problems
S Weiskirchen, SK Schröder, EM Buhl, R Weiskirchen - Cells, 2023 - mdpi.com
The cultivation of cells in a favorable artificial environment has become a versatile tool in
cellular and molecular biology. Cultured primary cells and continuous cell lines are …
cellular and molecular biology. Cultured primary cells and continuous cell lines are …
Efficient Therapy of Inflammatory Bowel Disease (IBD) with Highly Specific and Durable Targeted Ta2C Modified with Chondroitin Sulfate (TACS)
X Song, Q Huang, Y Yang, L Ma, W Liu… - Advanced …, 2023 - Wiley Online Library
Non‐invasive localization of lesions and specific targeted therapy are still the main
challenges for inflammatory bowel disease (IBD). Ta, as a medical metal element, has been …
challenges for inflammatory bowel disease (IBD). Ta, as a medical metal element, has been …