Involvement of lncRNAs in cancer cells migration, invasion and metastasis: cytoskeleton and ECM crosstalk

M Ahmad, LB Weiswald, L Poulain, C Denoyelle… - Journal of Experimental …, 2023 - Springer
Cancer is the main cause of death worldwide and metastasis is a major cause of poor
prognosis and cancer-associated mortality. Metastatic conversion of cancer cells is a …

Long non-coding RNAs in lung cancer: Unraveling the molecular modulators of MAPK signaling

MS Hussain, O Afzal, G Gupta, ASA Altamimi… - … -Research and Practice, 2023 - Elsevier
Lung cancer (LC) continues to pose a significant global medical burden, necessitating a
comprehensive understanding of its molecular foundations to establish effective treatment …

Long non-coding RNAs and complex diseases: from experimental results to computational models

X Chen, CC Yan, X Zhang, ZH You - Briefings in bioinformatics, 2017 - academic.oup.com
LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …

Long noncoding RNAs as biomarkers in cancer

L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …

TANRIC: an interactive open platform to explore the function of lncRNAs in cancer

J Li, L Han, P Roebuck, L Diao, L Liu, Y Yuan… - Cancer …, 2015 - aacrjournals.org
Long noncoding RNAs (lncRNA) have emerged as essential players in cancer biology.
Using recent large-scale RNA-seq datasets, especially those from The Cancer Genome …

Long non-coding RNA: its evolutionary relics and biological implications in mammals: a review

JK Dhanoa, RS Sethi, R Verma, JS Arora… - Journal of animal …, 2018 - Springer
The central dogma of gene expression propounds that DNA is transcribed to mRNA and
finally gets translated into protein. Only 2–3% of the genomic DNA is transcribed to protein …

Lung cancer epigenetics: from knowledge to applications

M Duruisseaux, M Esteller - Seminars in cancer biology, 2018 - Elsevier
Lung cancer is the leading cause of cancer-related mortality worldwide. Advances in our
understanding of the genomics of lung cancer have led to substantial progress in the …

Functions of lncRNA HOTAIR in lung cancer

G Loewen, J Jayawickramarajah, Y Zhuo… - Journal of hematology & …, 2014 - Springer
Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes.
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …

[HTML][HTML] Long non-coding RNAs: Mechanism of action and functional utility

SA Bhat, SM Ahmad, PT Mumtaz, AA Malik… - Non-coding RNA …, 2016 - Elsevier
Recent RNA sequencing studies have revealed that most of the human genome is
transcribed, but very little of the total transcriptomes has the ability to encode proteins. Long …

The functional role of long non-coding RNAs and epigenetics

J Cao - Biological procedures online, 2014 - Springer
Long non-coding RNAs (lncRNAs) are non-protein coding transcripts longer than 200
nucleotides. The post-transcriptional regulation is influenced by these lncRNAs by …