Toxicity of graphene-family nanoparticles: a general review of the origins and mechanisms

L Ou, B Song, H Liang, J Liu, X Feng, B Deng… - Particle and fibre …, 2016 - Springer
Due to their unique physicochemical properties, graphene-family nanomaterials (GFNs) are
widely used in many fields, especially in biomedical applications. Currently, many studies …

Translocation of (ultra)fine particles and nanoparticles across the placenta; a systematic review on the evidence of in vitro, ex vivo, and in vivo studies

E Bongaerts, TS Nawrot, T Van Pee, M Ameloot… - Particle and Fibre …, 2020 - Springer
Fetal development is a crucial window of susceptibility in which exposure may lead to
detrimental health outcomes at birth and later in life. The placenta serves as a gatekeeper …

Recent insights on indirect mechanisms in developmental toxicity of nanomaterials

BB Dugershaw, L Aengenheister, SSK Hansen… - Particle and Fibre …, 2020 - Springer
Background Epidemiological and animal studies provide compelling indications that
environmental and engineered nanomaterials (NMs) pose a risk for pregnancy, fetal …

Basal Ti level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2 nanoparticles in an ex vivo placental perfusion …

A Guillard, E Gaultier, C Cartier, L Devoille… - Particle and Fibre …, 2020 - Springer
Abstract Background Titanium dioxide (TiO 2) is broadly used in common consumer goods,
including as a food additive (E171 in Europe) for colouring and opacifying properties. The …

Plasma proteins facilitates placental transfer of polystyrene particles

MM Gruber, B Hirschmugl, N Berger, M Holter… - Journal of …, 2020 - Springer
Background Nanoparticles, which are exposed to biological fluids are rapidly interacting
with proteins and other biomolecules forming a corona. In addition to dimension, charge and …

Reproductive and developmental toxicity of carbon-based nanomaterials: a literature review

M Ema, KS Hougaard, A Kishimoto, K Honda - Nanotoxicology, 2016 - Taylor & Francis
We summarized the findings of reproductive and developmental toxicity studies on carbon-
based nanomaterials (CNMs). Placental transfer of fullerenes in rats and single-walled (SW) …

Bidirectional Transfer Study of Polystyrene Nanoparticles across the Placental Barrier in an ex Vivo Human Placental Perfusion Model

S Grafmueller, P Manser, L Diener… - Environmental …, 2015 - ehp.niehs.nih.gov
Background Nanoparticle exposure in utero might not be a major concern yet, but it could
become more important with the increasing application of nanomaterials in consumer and …

Progress and future of in vitro models to study translocation of nanoparticles

HM Braakhuis, SK Kloet, S Kezic, F Kuper… - Archives of …, 2015 - Springer
The increasing use of nanoparticles in products likely results in increased exposure of both
workers and consumers. Because of their small size, there are concerns that nanoparticles …

An advanced human in vitro co-culture model for translocation studies across the placental barrier

L Aengenheister, K Keevend, C Muoth… - Scientific reports, 2018 - nature.com
Although various drugs, environmental pollutants and nanoparticles (NP) can cross the
human placental barrier and may harm the develo** fetus, knowledge on predictive …

Nanoparticle transport across the placental barrier: pushing the field forward!

C Muoth, L Aengenheister, M Kucki, P Wick… - …, 2016 - Taylor & Francis
The human placenta is a multifunctional organ constituting the barrier between maternal and
fetal tissues. Nanoparticles can cross the placental barrier, and there is increasing evidence …