The genetics of bipolar disorder
FJA Gordovez, FJ McMahon - Molecular psychiatry, 2020 - nature.com
Bipolar disorder (BD) is one of the most heritable mental illnesses, but the elucidation of its
genetic basis has proven to be a very challenging endeavor. Genome-Wide Association …
genetic basis has proven to be a very challenging endeavor. Genome-Wide Association …
Psychiatric genetics and the structure of psychopathology
For over a century, psychiatric disorders have been defined by expert opinion and clinical
observation. The modern DSM has relied on a consensus of experts to define categorical …
observation. The modern DSM has relied on a consensus of experts to define categorical …
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
Diagnosis and management of bipolar disorders
FS Goes - bmj, 2023 - bmj.com
Bipolar disorders (BDs) are recurrent and sometimes chronic disorders of mood that affect
around 2% of the world's population and encompass a spectrum between severe elevated …
around 2% of the world's population and encompass a spectrum between severe elevated …
A hierarchical causal taxonomy of psychopathology across the life span.
We propose a taxonomy of psychopathology based on patterns of shared causal influences
identified in a review of multivariate behavior genetic studies that distinguish genetic and …
identified in a review of multivariate behavior genetic studies that distinguish genetic and …
Comorbidity of ADHD and adult bipolar disorder: A systematic review and meta-analysis
C Schiweck, G Arteaga-Henriquez, M Aichholzer… - Neuroscience & …, 2021 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) and Bipolar Disorder (BD) are common
mental disorders with a high degree of comorbidity. However, no systematic review with …
mental disorders with a high degree of comorbidity. However, no systematic review with …
Genetics and genomics of psychiatric disease
Large-scale genomic investigations have just begun to illuminate the molecular genetic
contributions to major psychiatric illnesses, ranging from small-effect-size common variants …
contributions to major psychiatric illnesses, ranging from small-effect-size common variants …
Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum
The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological
system that addresses shortcomings of traditional mental disorder diagnoses, including …
system that addresses shortcomings of traditional mental disorder diagnoses, including …
Culture and psychopathology: An attempt at reconsidering the role of social learning
This paper proposes a model for developmental psychopathology that is informed by recent
research suggestive of a single model of mental health disorder (the p factor) and seeks to …
research suggestive of a single model of mental health disorder (the p factor) and seeks to …
Systematic assessment of environmental risk factors for bipolar disorder: an umbrella review of systematic reviews and meta‐analyses
Objectives The pathophysiology of bipolar disorder is likely to involve both genetic and
environmental risk factors. In our study, we aimed to perform a systematic search of …
environmental risk factors. In our study, we aimed to perform a systematic search of …