Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for
more than half of all dementia cases in the elderly. Interestingly, the clinical manifestations of …

Ample evidence has demonstrated that sex steroid hormones, such as the potent estrogen
17β-estradiol (E2), affect hippocampal morphology, plasticity, and memory in male and …

Objective: To test the hypothesis that effects of estrogen-containing hormone therapy on
cognitive abilities differ between postmenopausal women near to, and further from …

Although ovarian hormones are thought to have a potential role in the well-known sex
difference in mood and anxiety disorders, the mechanisms through which ovarian hormone …

Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

There is ample empirical evidence to support the notion that the biological impacts of
estrogen extend beyond the gonads to other bodily systems, including the brain and …

The prevalence of left ventricular diastolic dysfunction (LVDD) sharply increases in women
after menopause and may lead to heart failure. While evidence suggests that estrogens …

Several lines of evidence have converged to indicate that memory formation involves
plasticity of dendritic spines in the medial prefrontal cortex (PFC) and the hippocampus …

While a great deal of research has been performed on the long-term genomic actions of
estrogens, their rapid effects and implications for learning and memory are less well …

The ovarian hormones 17β-estradiol (E 2) and progesterone (P 4) are potent modulators of
hippocampal memory formation. Both hormones have been demonstrated to enhance …