[HTML][HTML] Sustained proliferation in cancer: Mechanisms and novel therapeutic targets
Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …
Unraveling the mechanistic effects of electric field stimulation towards directing stem cell fate and function: A tissue engineering perspective
Electric field (EF) stimulation can play a vital role in eliciting appropriate stem cell response.
Such an approach is recently being established to guide stem cell differentiation through …
Such an approach is recently being established to guide stem cell differentiation through …
[HTML][HTML] Exosomes/microvesicles as a mechanism of cell-to-cell communication
Microvesicles (MVs) are circular fragments of membrane released from the endosomal
compartment as exosomes or shed from the surface membranes of most cell types. An …
compartment as exosomes or shed from the surface membranes of most cell types. An …
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
KW Orford, DT Scadden - Nature Reviews Genetics, 2008 - nature.com
The regulation of stem cell self-renewal must balance the regenerative needs of tissues that
persist throughout life with the potential for cell overgrowth, transformation and cancer. Here …
persist throughout life with the potential for cell overgrowth, transformation and cancer. Here …
Looking into the future: toward advanced 3D biomaterials for stem‐Cell‐based regenerative medicine
Z Liu, M Tang, J Zhao, R Chai, J Kang - Advanced Materials, 2018 - Wiley Online Library
Stem‐cell‐based therapies have the potential to provide novel solutions for the treatment of
a variety of diseases, but the main obstacles to such therapies lie in the uncontrolled …
a variety of diseases, but the main obstacles to such therapies lie in the uncontrolled …
Biomaterials for stem cell differentiation
E Dawson, G Mapili, K Erickson, S Taqvi… - Advanced drug delivery …, 2008 - Elsevier
The promise of cellular therapy lies in the repair of damaged organs and tissues in vivo as
well as generating tissue constructs in vitro for subsequent transplantation. Unfortunately …
well as generating tissue constructs in vitro for subsequent transplantation. Unfortunately …
Stem cells: A revolution in therapeutics—Recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies
M Mimeault, R Hauke, SK Batra - Clinical Pharmacology & …, 2007 - Wiley Online Library
Basic and clinical research accomplished during the last few years on embryonic, fetal,
amniotic, umbilical cord blood, and adult stem cells has constituted a revolution in …
amniotic, umbilical cord blood, and adult stem cells has constituted a revolution in …
Decellularized ECM hydrogels: prior use considerations, applications, and opportunities in tissue engineering and biofabrication
Tissue development, wound healing, pathogenesis, regeneration, and homeostasis rely
upon coordinated and dynamic spatial and temporal remodeling of extracellular matrix …
upon coordinated and dynamic spatial and temporal remodeling of extracellular matrix …
Concise review: no breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder‐free; medium with fetal calf …
F Mannello, GA Tonti - Stem cells, 2007 - academic.oup.com
The choice of an optimal strategy of stem cell culture is at the moment an impossible task,
and the elaboration of a culture medium adapted to the production of embryonic and adult …
and the elaboration of a culture medium adapted to the production of embryonic and adult …
Advances in signaling in vertebrate regeneration as a prelude to regenerative medicine
CL Stoick-Cooper, RT Moon… - Genes & …, 2007 - genesdev.cshlp.org
While all animals have evolved strategies to respond to injury and disease, their ability to
functionally recover from loss of or damage to organs or appendages varies widely damage …
functionally recover from loss of or damage to organs or appendages varies widely damage …