[HTML][HTML] Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

MA Feitelson, A Arzumanyan, RJ Kulathinal… - Seminars in cancer …, 2015 - Elsevier
Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

Unraveling the mechanistic effects of electric field stimulation towards directing stem cell fate and function: A tissue engineering perspective

G Thrivikraman, SK Boda, B Basu - Biomaterials, 2018 - Elsevier
Electric field (EF) stimulation can play a vital role in eliciting appropriate stem cell response.
Such an approach is recently being established to guide stem cell differentiation through …

[HTML][HTML] Exosomes/microvesicles as a mechanism of cell-to-cell communication

G Camussi, MC Deregibus, S Bruno, V Cantaluppi… - Kidney international, 2010 - Elsevier
Microvesicles (MVs) are circular fragments of membrane released from the endosomal
compartment as exosomes or shed from the surface membranes of most cell types. An …

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

KW Orford, DT Scadden - Nature Reviews Genetics, 2008 - nature.com
The regulation of stem cell self-renewal must balance the regenerative needs of tissues that
persist throughout life with the potential for cell overgrowth, transformation and cancer. Here …

Looking into the future: toward advanced 3D biomaterials for stem‐Cell‐based regenerative medicine

Z Liu, M Tang, J Zhao, R Chai, J Kang - Advanced Materials, 2018 - Wiley Online Library
Stem‐cell‐based therapies have the potential to provide novel solutions for the treatment of
a variety of diseases, but the main obstacles to such therapies lie in the uncontrolled …

Biomaterials for stem cell differentiation

E Dawson, G Mapili, K Erickson, S Taqvi… - Advanced drug delivery …, 2008 - Elsevier
The promise of cellular therapy lies in the repair of damaged organs and tissues in vivo as
well as generating tissue constructs in vitro for subsequent transplantation. Unfortunately …

Stem cells: A revolution in therapeutics—Recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies

M Mimeault, R Hauke, SK Batra - Clinical Pharmacology & …, 2007 - Wiley Online Library
Basic and clinical research accomplished during the last few years on embryonic, fetal,
amniotic, umbilical cord blood, and adult stem cells has constituted a revolution in …

Decellularized ECM hydrogels: prior use considerations, applications, and opportunities in tissue engineering and biofabrication

J Kort-Mascort, S Flores-Torres, O Peza-Chavez… - Biomaterials …, 2023 - pubs.rsc.org
Tissue development, wound healing, pathogenesis, regeneration, and homeostasis rely
upon coordinated and dynamic spatial and temporal remodeling of extracellular matrix …

Concise review: no breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder‐free; medium with fetal calf …

F Mannello, GA Tonti - Stem cells, 2007 - academic.oup.com
The choice of an optimal strategy of stem cell culture is at the moment an impossible task,
and the elaboration of a culture medium adapted to the production of embryonic and adult …

Advances in signaling in vertebrate regeneration as a prelude to regenerative medicine

CL Stoick-Cooper, RT Moon… - Genes & …, 2007 - genesdev.cshlp.org
While all animals have evolved strategies to respond to injury and disease, their ability to
functionally recover from loss of or damage to organs or appendages varies widely damage …