The need for consistency in analytical method development reinforces the dependence of
pharmaceutical product development and manufacturing on robust analytical data. The …

Although Vinorelbine (VOB) is a powerful anticancer medication, it inevitably has a number
of adverse effects. Therefore, identifying this medication in biological samples is crucial for …

It is widely accepted that cancer, the second leading cause of death, is a morbidity with big
impacts on the global health. In the last few years, chemo-therapeutic treatment continually …

This work represents a combined approach of green chemistry and analytical Quality-by-
Design principles for develo** sustainable HPLC-DAD methods with high operational …

The electrochemical behavior and direct quantitative determination of paclitaxel, a poorly
soluble drug made into microemulsion, were researched by cyclic voltammetry in acetate …

Abstract Design of Experiment (DoE) is an effective methodology for studying the
relationship between variables and their dependent responses. In this study, DoE was …

Atazanavir (ATV) is widely used as anti-HIV agent having poor aqueous solubility needs to
modulate novel drug delivery system to enhance therapeutic efficiency and safety. The main …

Purpose Non-small cell lung cancer (NSCLC) is an aggressive tumor with high mortality and
poor prognosis. In this study, we designed a liposome encapsulating polymeric micelles …

Abstract Design of experiment (DoE) techniques have been widely used in the field of
chromatographic parameters optimization as a valuable tool. A systematic literature review …