Unresponsiveness≠ unconsciousness
Consciousness is subjective experience. During both sleep and anesthesia consciousness
is common, evidenced by dreaming. A defining feature of dreaming is that, while conscious …
is common, evidenced by dreaming. A defining feature of dreaming is that, while conscious …
American society for enhanced recovery and perioperative quality initiative joint consensus statement on the role of neuromonitoring in perioperative outcomes …
Electroencephalographic (EEG) monitoring to indicate brain state during anesthesia has
become widely available. It remains unclear whether EEG-guided anesthesia influences …
become widely available. It remains unclear whether EEG-guided anesthesia influences …
BIS-guided anesthesia decreases postoperative delirium and cognitive decline
Background: Previous clinical trials and animal experiments have suggested that long-
lasting neurotoxicity of general anesthetics may lead to postoperative cognitive dysfunction …
lasting neurotoxicity of general anesthetics may lead to postoperative cognitive dysfunction …
Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction
Background Postoperative delirium in elderly patients is a frequent complication and
associated with poor outcome. The aim of this parallel group study was to determine …
associated with poor outcome. The aim of this parallel group study was to determine …
Prevention of intraoperative awareness in a high-risk surgical population
MS Avidan, E Jacobsohn, D Glick… - … England Journal of …, 2011 - Mass Medical Soc
Background Unintended intraoperative awareness, which occurs when general anesthesia
is not achieved or maintained, affects up to 1% of patients at high risk for this complication …
is not achieved or maintained, affects up to 1% of patients at high risk for this complication …
Anaesthetic depth and complications after major surgery: an international, randomised controlled trial
TG Short, D Campbell, C Frampton, MTV Chan… - The Lancet, 2019 - thelancet.com
Background An association between increasing anaesthetic depth and decreased
postoperative survival has been shown in observational studies; however, evidence from …
postoperative survival has been shown in observational studies; however, evidence from …
Minimum alveolar concentration: ongoing relevance and clinical utility
Since its introduction in 1965, minimum alveolar concentration (MAC) has served as the
standard measure of potency for volatile anaesthetic agents. It is defined as the minimum …
standard measure of potency for volatile anaesthetic agents. It is defined as the minimum …
Platelet counts, acute kidney injury, and mortality after coronary artery bypass grafting surgery
MD Kertai, S Zhou, JA Karhausen, M Cooter… - …, 2016 - pmc.ncbi.nlm.nih.gov
BACKGROUND Cardiac surgery requiring cardiopulmonary bypass is associated with
platelet activation. Since platelets are increasingly recognized as important effectors of …
platelet activation. Since platelets are increasingly recognized as important effectors of …
Anesthetic management during cardiopulmonary bypass: a systematic review
AE Barry, MA Chaney, MJ London - Anesthesia & Analgesia, 2015 - journals.lww.com
Cardiopulmonary bypass (CPB) required for cardiac surgery presents unique challenges to
the cardiac anesthesiologist responsible for providing the 3 most basic facets of any …
the cardiac anesthesiologist responsible for providing the 3 most basic facets of any …
Frailty, aging, and cardiovascular surgery
A Graham, CH Brown IV - Anesthesia & Analgesia, 2017 - journals.lww.com
Enarrative REVIEW ARTICLE criteria were soon validated in the Women's Health and Aging
Study, in which the prevalence and outcomes associated with frailty were similar, and latent …
Study, in which the prevalence and outcomes associated with frailty were similar, and latent …