The immunology of sepsis
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to an infection. This recently implemented definition does not capture the …
response to an infection. This recently implemented definition does not capture the …
Outcomes after critical illness
MS Herridge, É Azoulay - New England Journal of Medicine, 2023 - Mass Medical Soc
Outcomes after Critical Illness | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American …
SA McClave, BE Taylor, RG Martindale… - JPEN. Journal of …, 2016 - europepmc.org
Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically
Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and …
Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and …
The immunopathology of sepsis and potential therapeutic targets
T van der Poll, FL van de Veerdonk… - Nature Reviews …, 2017 - nature.com
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. In sepsis, the immune response that is initiated by an invading …
host response to infection. In sepsis, the immune response that is initiated by an invading …
Sepsis-induced immunosuppression
LK Torres, P Pickkers… - Annual review of …, 2022 - annualreviews.org
Sepsis is expected to have a substantial impact on public health and cost as its prevalence
increases. Factors contributing to increased prevalence include a progressively aging …
increases. Factors contributing to increased prevalence include a progressively aging …
Sepsis and septic shock
RS Hotchkiss, LL Moldawer, SM Opal… - Nature reviews Disease …, 2016 - nature.com
For more than two decades, sepsis was defined as a microbial infection that produces fever
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …
Cytokine storm—definition, causes, and implications
D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
The human innate and adaptive immune systems consist of effector cells producing
cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a …
cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a …
The immune system's role in sepsis progression, resolution, and long‐term outcome
MJ Delano, PA Ward - Immunological reviews, 2016 - Wiley Online Library
Sepsis occurs when an infection exceeds local tissue containment and induces a series of
dysregulated physiologic responses that result in organ dysfunction. A subset of patients …
dysregulated physiologic responses that result in organ dysfunction. A subset of patients …
Innate immune responses to trauma
Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
Up to 49% of certain types of cancer are attributed to obesity, and potential mechanisms
include overproduction of hormones, adipokines, and insulin. Cytotoxic immune cells …
include overproduction of hormones, adipokines, and insulin. Cytotoxic immune cells …