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Butyrate producers,“The Sentinel of Gut”: Their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics
Gut-microbial butyrate is a short-chain fatty acid (SCFA) of significant physiological
importance than the other major SCFAs (acetate and propionate). Most butyrate producers …
importance than the other major SCFAs (acetate and propionate). Most butyrate producers …
New approaches and procedures for cancer treatment: Current perspectives
DT Debela, SGY Muzazu, KD Heraro… - SAGE open …, 2021 - journals.sagepub.com
Cancer is a global health problem responsible for one in six deaths worldwide. Treating
cancer has been a highly complex process. Conventional treatment approaches, such as …
cancer has been a highly complex process. Conventional treatment approaches, such as …
Genetic and biological hallmarks of colorectal cancer
Colorectal cancer has served as a genetic and biological paradigm for the evolution of solid
tumors, and these insights have illuminated early detection, risk stratification, prevention …
tumors, and these insights have illuminated early detection, risk stratification, prevention …
Altered metabolism in cancer: Insights into energy pathways and therapeutic targets
M Tufail, CH Jiang, N Li - Molecular Cancer, 2024 - Springer
Cancer cells undergo significant metabolic reprogramming to support their rapid growth and
survival. This study examines important metabolic pathways like glycolysis, oxidative …
survival. This study examines important metabolic pathways like glycolysis, oxidative …
FTO m6A demethylase in obesity and cancer: implications and underlying molecular mechanisms
Fat mass and obesity-associated protein (FTO) is the first reported RNA N6-
methyladenosine (m6A) demethylase in eukaryotic cells. m6A is considered as the most …
methyladenosine (m6A) demethylase in eukaryotic cells. m6A is considered as the most …
Advances in anti-cancer effects and underlying mechanisms of marine algae polysaccharides
Cancer is a leading cause of death in both develo** and developed countries. With the
increase in the average global life expectancy, it has become a major health problem and …
increase in the average global life expectancy, it has become a major health problem and …
Copper promotes tumorigenesis by activating the PDK1‐AKT oncogenic pathway in a copper transporter 1 dependent manner
Copper plays pivotal roles in metabolic homoeostasis, but its potential role in human
tumorigenesis is not well defined. Here, it is revealed that copper activates the …
tumorigenesis is not well defined. Here, it is revealed that copper activates the …
Nanomaterials for theranostics: recent advances and future challenges
The field of nanomedicines has expanded significantly in recent years in the breadth of
compounds under development as well as in the types of technology that are being applied …
compounds under development as well as in the types of technology that are being applied …
Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth
JA Kashatus, A Nascimento, LJ Myers, A Sher… - Molecular cell, 2015 - cell.com
Ras is mutated in up to 30% of cancers, including 90% of pancreatic ductal
adenocarcinomas, causing it to be constitutively GTP-bound, and leading to activation of …
adenocarcinomas, causing it to be constitutively GTP-bound, and leading to activation of …
Cholesteryl ester accumulation induced by PTEN loss and PI3K/AKT activation underlies human prostate cancer aggressiveness
Altered lipid metabolism is increasingly recognized as a signature of cancer cells. Enabled
by label-free Raman spectromicroscopy, we performed quantitative analysis of lipogenesis …
by label-free Raman spectromicroscopy, we performed quantitative analysis of lipogenesis …