Tuberculosis still remains one of the most common, communicable, and leading deadliest
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …

Imidazoles are one of the most promising and vigorously pursued areas of contemporary
antifungal chemotherapy depicting broad spectrum and potent activity. They have relatively …

Carbon-carbon coupling play a vital role in the synthetic field of organic chemistry. Two
novel pyridine derivatives: 3-bromo-5-(2, 5-difluorophenyl) pyridine (1) and 3, 5-bis …

Herein, we report the synthesis and biological evaluation of [Pd (L)(OH 2) Cl] complex
(where L= 2, 2′-(pyridin-2-ylmethylene) bis (5, 5-dimethylcyclohexane-1, 3-dione) as a …

A series of novel pyrazolo [3, 4-b] pyridine and pyrimidine functionalized 1, 2, 3-triazole
derivatives 8a–g and 9a–g were prepared starting from 6-trifluoromethylpyridine-2 (1H) one …

3H-1, 3, 4-Oxadiazole-2-thione and 3H-1, 3, 4-oxadiazol-2-one derivatives were
synthesized and tested for their in vitro antimycobacterial activity. Oxadiazolone derivatives …

New bis-imidazole derivatives have been synthesized and their antifungal and
antimycobacterial activity was determined. Almost all compounds exhibited a moderate to …

Amino substituted benzothiazoles 2a–l and 2-chloropyridine-3-carboxylic acid 3 were used
to prepare 2-[N-(substitutedbenzothiazolyl) amino] pyridine-3-carboxylic acids (4a–l) in 2 …

Objectives: To synthesize new antimycobacterial and antifungal drugs that act by binding to
sterol 14α-demethylase (14DM) and to characterize the drug–target protein interactions …

A series of nicotinic acid benzylidene hydrazide derivatives (1–18) was synthesized and
tested in vitro for biological evaluations. The antimycobacterial activity results indicated that …