Role of endogenous lipopolysaccharides in neurological disorders
Lipopolysaccharide (LPS) is a cell-wall immunostimulatory endotoxin component of Gram-
negative bacteria. A growing body of evidence reveals that alterations in the bacterial …
negative bacteria. A growing body of evidence reveals that alterations in the bacterial …
[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …
Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker
Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) III protein uniquely found
in astrocytes in the central nervous system (CNS), non-myelinating Schwann cells in the …
in astrocytes in the central nervous system (CNS), non-myelinating Schwann cells in the …
[HTML][HTML] Donepezil regulates LPS and Aβ-stimulated neuroinflammation through MAPK/NLRP3 inflammasome/STAT3 signaling
The acetylcholinesterase inhibitors donepezil and rivastigmine have been used as
therapeutic drugs for Alzheimer's disease (AD), but their effects on LPS-and Aβ-induced …
therapeutic drugs for Alzheimer's disease (AD), but their effects on LPS-and Aβ-induced …
NRF2 as a therapeutic target in neurodegenerative diseases
Increased reactive oxygen species production and oxidative stress have been implicated in
the pathogenesis of numerous neurodegenerative conditions including among others …
the pathogenesis of numerous neurodegenerative conditions including among others …
Porphyromonas gingivalis lipopolysaccharide induces cognitive dysfunction, mediated by neuronal inflammation via activation of the TLR4 signaling pathway in …
J Zhang, C Yu, X Zhang, H Chen, J Dong, W Lu… - Journal of …, 2018 - Springer
Background Porphyromonas gingivalis lipopolysaccharide (P. gingivalis-LPS) is one of the
major pathogenic factors of chronic periodontitis (CP). Few reports on the correlation …
major pathogenic factors of chronic periodontitis (CP). Few reports on the correlation …
Crosstalk between neuroinflammation and oxidative stress in epilepsy
The roles of both neuroinflammation and oxidative stress in the pathophysiology of epilepsy
have begun to receive considerable attention in recent years. However, these concepts are …
have begun to receive considerable attention in recent years. However, these concepts are …