Interactions between the microbiota and pathogenic bacteria in the gut
The microbiome has an important role in human health. Changes in the microbiota can
confer resistance to or promote infection by pathogenic bacteria. Antibiotics have a profound …
confer resistance to or promote infection by pathogenic bacteria. Antibiotics have a profound …
Gut microbiota and colonization resistance against bacterial enteric infection
QR Ducarmon, RD Zwittink, BVH Hornung… - Microbiology and …, 2019 - Am Soc Microbiol
The gut microbiome is critical in providing resistance against colonization by exogenous
microorganisms. The mechanisms via which the gut microbiota provide colonization …
microorganisms. The mechanisms via which the gut microbiota provide colonization …
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota
Most mucosal surfaces of the mammalian body are colonized by microbial communities
(“microbiota”). A high density of commensal microbiota inhabits the intestine and shields …
(“microbiota”). A high density of commensal microbiota inhabits the intestine and shields …
Salmonella, the host and disease: a brief review
Salmonella species cause substantial morbidity, mortality and burden of disease globally.
Infections with Salmonella species cause multiple clinical syndromes. Central to the …
Infections with Salmonella species cause multiple clinical syndromes. Central to the …
Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota
P Thiennimitr, SE Winter, MG Winter… - Proceedings of the …, 2011 - National Acad Sciences
Conventional wisdom holds that microbes support their growth in vertebrate hosts by
exploiting a large variety of nutrients. We show here that use of a specific nutrient …
exploiting a large variety of nutrients. We show here that use of a specific nutrient …
Type III secretion systems and disease
Type III secretion systems (T3SSs) are complex bacterial structures that provide gram-
negative pathogens with a unique virulence mechanism enabling them to inject bacterial …
negative pathogens with a unique virulence mechanism enabling them to inject bacterial …
Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa
The gut mucosal epithelium separates the host from the microbiota, but enteropathogens
such as Salmonella Typhimurium (S. Tm) can invade and breach this barrier. Defenses …
such as Salmonella Typhimurium (S. Tm) can invade and breach this barrier. Defenses …
Commensal Enterobacteriaceae protect against Salmonella colonization through oxygen competition
Neonates are highly susceptible to infection with enteric pathogens, but the underlying
mechanisms are not resolved. We show that neonatal chick colonization with Salmonella …
mechanisms are not resolved. We show that neonatal chick colonization with Salmonella …
Oxygen as a driver of gut dysbiosis
Abstract Changes in the composition of gut-associated microbial communities may underlie
many inflammatory and allergic diseases. However, the processes that help maintain a …
many inflammatory and allergic diseases. However, the processes that help maintain a …
Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection
I Sekirov, NM Tam, M Jogova, ML Robertson… - Infection and …, 2008 - Am Soc Microbiol
Intestinal microbiota comprises microbial communities that reside in the gastrointestinal tract
and are critical to normal host physiology. Understanding the microbiota's role in host …
and are critical to normal host physiology. Understanding the microbiota's role in host …