The development and continuous improvement of high-throughput sequencing platforms
have stimulated interest in the study of complex microbial communities. Currently, the most …

Advances in DNA sequencing technology have vastly improved the ability of researchers to
explore the microbial inhabitants of the human body. Unfortunately, while these studies have …

Land plants associate with a root microbiota distinct from the complex microbial community
present in surrounding soil. The microbiota colonizing the rhizosphere (immediately …

Abstract Ribosomal Database Project (RDP; http://rdp. cme. msu. edu/) provides the
research community with aligned and annotated rRNA gene sequence data, along with tools …

Background & Aims Altered interactions between the mucosal immune system and intestinal
microbiota contribute to pathogenesis of inflammatory bowel diseases (IBD). It is not clear …

Type 1 diabetes mellitus (T1DM) is a chronic immune-mediated disease with a subclinical
prodromal period, characterized by selective loss of insulin-producing-β cells in the …

The Amazon rainforest is the Earth's largest reservoir of plant and animal diversity, and it has
been subjected to especially high rates of land use change, primarily to cattle pasture. This …

A wide array of microorganisms survive and thrive in extreme environments. However, we
know little about the patterns of, and controls over, their large-scale ecological distribution …

Demands for faster and more accurate methods to analyze microbial communities from
natural and clinical samples have been increasing in the medical and healthcare industry …

Understanding the Maxam-Gilbert and Sanger sequencing as the first generation, in recent
years there has been an explosion of newly-developed sequencing strategies, which are …