Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

The placenta is a transient fetal organ that plays a critical role in the health and wellbeing of
both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it …

Beginning in the first trimester, fetally derived extravillous trophoblasts (EVTs) invade the
uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels …

Preeclampsia (PE) is a leading cause for peripartal morbidity, especially if develo** early
in gestation. To enable prophylaxis in the prevention of PE, pregnancies at risk of PE must …

Neutrophil extracellular traps (NETs), crucial in immune defense mechanisms, are
renowned for their propensity to expel decondensed chromatin embedded with inflammatory …

Objective Preeclampsia is a common and serious complication of pregnancy, posing a
threat to maternal and fetal safety due to the lack of effective biomarkers and treatment …

Biopsy, including tissue and liquid biopsy, offers comprehensive and real-time physiological
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …

Preeclampsia (PE) is the leading cause of maternal and fetal mortality globally and may
trigger dementia later in life in mothers and their offspring. However, the etiological drivers …

Adoption of high-content omic technologies in clinical studies, coupled with computational
methods, has yielded an abundance of candidate biomarkers. However, translating such …

Liquid biopsies provide a means for the profiling of cell-free RNAs secreted by cells
throughout the body. Although well-annotated coding and non-coding transcripts in blood …