Challenges and opportunities for using big health care data to advance medical science and public health

SM Shortreed, AJ Cook, RY Coley… - American journal of …, 2019‏ - academic.oup.com
Methodological advancements in epidemiology, biostatistics, and data science have
strengthened the research world's ability to use data captured from electronic health records …

Longitudinal data subject to irregular observation: A review of methods with a focus on visit processes, assumptions, and study design

EM Pullenayegum, LSH Lim - Statistical methods in medical …, 2016‏ - journals.sagepub.com
When data are collected longitudinally, measurement times often vary among patients. This
is of particular concern in clinic-based studies, for example retrospective chart reviews …

[ספר][B] Joint modeling of longitudinal and time-to-event data

R Elashoff, N Li - 2016‏ - taylorfrancis.com
Longitudinal studies often incur several problems that challenge standard statistical
methods for data analysis. These problems include non-ignorable missing data in …

[ספר][B] Statistical analysis of panel count data

J Sun, X Zhao - 2013‏ - Springer
Panel count data occur in studies that concern recurrent events, or event history studies,
when study subjects are observed only at discrete time points. By recurrent events, we mean …

On the nature of informative presence bias in analyses of electronic health records

G McGee, S Haneuse, BA Coull, MG Weisskopf… - …, 2022‏ - journals.lww.com
Electronic health records (EHRs) offer unprecedented opportunities to answer
epidemiologic questions. However, unlike in ordinary cohort studies or randomized trials …

Randomized trials with repeatedly measured outcomes: handling irregular and potentially informative assessment times

EM Pullenayegum, DO Scharfstein - Epidemiologic reviews, 2022‏ - academic.oup.com
Randomized trials are often designed to collect outcomes at fixed points in time after
randomization. In practice, the number and timing of outcome assessments can vary among …

Joint modeling and analysis of longitudinal data with informative observation times

Y Liang, W Lu, Z Ying - Biometrics, 2009‏ - academic.oup.com
In analysis of longitudinal data, it is often assumed that observation times are predetermined
and are the same across study subjects. Such an assumption, however, is often violated in …

Semiparametric regression analysis of longitudinal data with informative observation times

J Sun, DH Park, L Sun, X Zhao - Journal of the American Statistical …, 2005‏ - Taylor & Francis
Statistical analysis of longitudinal data has been discussed by many authors, and a number
of methods have been proposed. Most of the research have focused on situations where …

Joint analysis of longitudinal data with informative observation times and a dependent terminal event

L Sun, X Song, J Zhou, L Liu - Journal of the American Statistical …, 2012‏ - Taylor & Francis
In many longitudinal studies, repeated measures are often correlated with observation times.
Also, there may exist a dependent terminal event such as death that stops the follow-up. In …

Joint models of longitudinal data and recurrent events with informative terminal event

S Kim, D Zeng, L Chambless, Y Li - Statistics in biosciences, 2012‏ - Springer
This article presents semiparametric joint models to analyze longitudinal data with recurrent
events (eg multiple tumors, repeated hospital admissions) and a terminal event such as …