The peripheral anionic site of acetylcholinesterase lies at the entrance to the active site
gorge. It is composed of five residues (Tyr 70, Asp 72, Tyr 121, Trp 279 and Tyr 334; …

This article focuses on local protein synthesis as a basis for maintaining axoplasmic mass,
and expression of plasticity in axons and terminals. Recent evidence of discrete ribosomal …

Acetylcholinesterase (AChE, EC3. 1.1. 7) functions in nerve impulse transmission, and
possibly as a cell adhesion factor during neurite outgrowth. These functions predicted that a …

Organophosphate poisonings are not uncommon, and are the leading cause of death in
suicide patients in Taiwan. Acute cholinergic crisis caused by the inhibition of synaptic …

The association between the congenital absence of colonic ganglion cells and an increased
acetylcholinesterase (AChE) expression in the affected tissue is of diagnostic importance in …

Acetylcholinesterase (AChE) is the enzyme that hydrolyzes the neurotransmitter
acetylcholine at cholinergic synapses and neuromuscular junctions. However, results from …

The concept of an electrostatic motif on the surface of biological macromolecules as a
definite topographical pattern of electrostatic potentials in three-dimensional space, provides …

Dorsal root ganglion (DRG) neurons show a transient peak expression of
acetylcholinesterase (AChE) during periods of axonal outgrowth prior to synaptogenesis …

There is accumulating evidence that acetylcholinesterase has secondary noncholinergic
functions, related to adhesion, differentiation, and the deposition of β-amyloid in Alzheimer's …

In this study neurite outgrowth from cultured hippocampal neurones was increased by
addition of acetylcholinesterase acting in a non-cholinergic manner. Only monomeric …