Background The candidate malaria vaccine RTS, S/AS01 is being evaluated in order to
inform a decision regarding its inclusion in routine vaccination schedules. Methods We …

Background Malaria risk can vary markedly between households in the same village, or
between villages, but the determinants of this “micro-epidemiological” variation in malaria …

Background The candidate malaria vaccine RTS, S/AS01E has entered phase 3 trials, but
data on long-term outcomes are limited. Methods For 4 years, we followed children who had …

Abstract Purpose of Review Global malaria elimination has little chance of success without
an effective vaccine. The first malaria vaccine, RTS, S/AS01e, demonstrated moderate …

Background Insecticide-treated bed nets (ITNs) are the cornerstone of malaria control in sub-
Saharan Africa but their effectiveness may be compromised by the spread of pyrethroid …

Background At the local level, malaria transmission clusters in hotspots, which may be a
group of households that experience higher than average exposure to infectious …

Over the last decades, malaria has declined substantially in The Gambia but its transmission
has not been interrupted. In order to better target control interventions, it is essential to …

Abstract Background Within affected communities, Plasmodium falciparum infections may be
skewed in distribution such that single or small clusters of households consistently harbour a …

The experimental malaria vaccine ChAd63 MVA ME-TRAP previously showed protective
efficacy against Plasmodium falciparum infection in Phase IIa sporozoite challenge studies …

Background The aim of this study was to determine the incidence and seasonal pattern of
malaria in children in South-West Burkina Faso, and to compare, in a randomized trial …