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Towards network-guided neuromodulation for epilepsy
Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …
research to identify critical nodes within dynamic epileptic networks with the aim to target …
Unearthing the mechanisms of responsive neurostimulation for epilepsy
Responsive neurostimulation (RNS) is an effective therapy for people with drug-resistant
focal epilepsy. In clinical trials, RNS therapy results in a meaningful reduction in median …
focal epilepsy. In clinical trials, RNS therapy results in a meaningful reduction in median …
Deep brain stimulation of symptom-specific networks in Parkinson's disease
Abstract Deep Brain Stimulation can improve tremor, bradykinesia, rigidity, and axial
symptoms in patients with Parkinson's disease. Potentially, improving each symptom may …
symptoms in patients with Parkinson's disease. Potentially, improving each symptom may …
[HTML][HTML] Lead-DBS v3. 0: Map** deep brain stimulation effects to local anatomy and global networks
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …
Map** dysfunctional circuits in the frontal cortex using deep brain stimulation
Frontal circuits play a critical role in motor, cognitive and affective processing, and their
dysfunction may result in a variety of brain disorders. However, exactly which frontal …
dysfunction may result in a variety of brain disorders. However, exactly which frontal …
Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia
Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …
Hypothalamic deep brain stimulation augments walking after spinal cord injury
A spinal cord injury (SCI) disrupts the neuronal projections from the brain to the region of the
spinal cord that produces walking, leading to various degrees of paralysis. Here, we aimed …
spinal cord that produces walking, leading to various degrees of paralysis. Here, we aimed …
Proceedings of the eighth annual deep brain stimulation think tank: advances in optogenetics, ethical issues affecting DBS research, neuromodulatory approaches for …
We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to
address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters …
address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters …
Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation
The pathophysiology of dystonic tremor and essential tremor remains partially understood.
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …
In patients with medication-refractory dystonic tremor or essential tremor, deep brain …
White matter variability, cognition, and disorders: a systematic review
Inter-individual differences can inform treatment procedures and—if accounted for—have
the potential to significantly improve patient outcomes. However, when studying brain …
the potential to significantly improve patient outcomes. However, when studying brain …